Protein

MCA_01839_1

Length
1,370 amino acids


Browser: contigA:5626229-5630342+

RNA-seq: read pairs 1336, FPKM 12.0, percentile rank 29.2% (100% = highest expression)

Protein function

SGD closest match:S000004363ROM2RHO1 GDP-GTP exchange protein 2
CGD closest match:CAL0000177920ROM2Rho family guanine nucleotide exchange factor

Protein alignments

%idAln lengthE-value
MIA_00394_137.33%5847e-82MIA_00394_1
A0A0J9XGJ0_GEOCN32.98%3825e-40Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA15s00648g PE=4 SV=1
UniRef50_A0A0J9XGJ032.98%3821e-36Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XGJ0_GEOCN
A0A060TFX0_BLAAD25.51%5416e-25ARAD1D26444p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26444g PE=4 SV=1
A0A167CRN4_9ASCO22.01%5775e-18Rho family guanine nucleotide exchange factor ROM2 OS=Sugiyamaella lignohabitans GN=ROM2 PE=4 SV=1
ROM2_YEAST22.40%3087e-09RHO1 GDP-GTP exchange protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ROM2 PE=1 SV=1
Q6C661_YARLI22.12%3398e-08YALI0E12155p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E12155g PE=4 SV=1
A0A1E4TD89_9ASCO23.30%3392e-07Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_46140 PE=4 SV=1
A0A1E3PFC6_9ASCO20.75%2411e-06Dbl homology domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84112 PE=4 SV=1
Q5AH90_CANAL20.82%3894e-06Rho family guanine nucleotide exchange factor OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ROM2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0208

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1370

Detailed signature matches

    1. SSF48065 (DBL homol...)
    2. PF00621 (RhoGEF)
    3. PS50010 (DH_2)
    1. PF00780 (CNH)
    2. PS50219 (CNH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_01839_1
MASYNNYNDGNDSSAGTNSLAPDSSNTIQNYPAFPISRSASPSLPLPSSSSKSRQYSLSLDIPATKNAYARISQIAPVLP
LSPLKSSTEETHPNIYQQQDELEENQEEGKPINPFLNSPLSFHQSQPSTSEFQFQQEEINPSLDGSHPSYSLTPDPSDSS
SSINDMNSNNNNYASPSQSPDINIYAGQKLPPTPWKDDDDCDQDPSSTLGSSVSSSPFKLNKNKNMASNTSILPHSPISP
TYNNTSPGKSQQANKMLTPILTADLQRTPSAPEPFSINKITAQSAKLSINTSINSAAQQRTPKQYAPVLERSQSASATSL
GLHPAPSFTSSTNSSSDCLASPTSVYSRHGSVSNELDPISAELSAIHVKQNSGAWHEDWNISEEVLAELPEDVIKFQSEL
HNFIQQEENYVNGLKVFFLVFKGDKPIHVVIDNQINRDLLVKTLFDPLKPILELNKTLLLKPFLDLQAQGREKNNPYLQF
DAQAVADWLQNIKEPFSQFAKLSISADYIIKEQKATNDRFKNLINSLNSQAKKHSNKDFDSLMHSTRTRFGLYTSHFNQL
LKLIRRNEGEPRICSGDVQKTINLIEECTKRCNALMAEYDHFQRVEGNILEMSLMERRLNFKRDQDKINFALSAQNGRPP
HEKILEKEIFRKSSFEPATVLLFDHMLVIVKKIKYDDWKILEPIAHLELLRIESLEEPAQLKKSDQLAAAVRKHSTNNSR
VNGGVKNFQSQLGSIDTKNSISPSRSISNFTVSELTSVQSAPSANSSNHPSSPSSPDSSFVNHSPSMGSSSSVTTPTLDS
FPPSPQLEQKPSPQSQLNLTPTPSLSTPLRPTNSLVVDLAKSNKYADKKSFFPVRFTNLKTGKQLKFYFQTRQDRKNFSD
NLISAKEQYRLKAFHECRVPLGLKVLDQSSFPLGMGIDPNYTNSPSNYVGGDAVDRALNMYPKDSPSKKPFVASTVNCAF
DMVVSNETLTFLGSNSGLFGARHVTSPSGEEAPLVWKQISNEPCITQIEGHEKPNVLFILTNSQLMYLKLNEVVLFLLSP
DGKMQIPITKPQLIAENIDCFKTGYFNGKLMLFFSSSSMAVDKSEVTCYEVALKPKHDGKSKSFKSMFKSREAKPYDEFL
HKPISHDSHLFSPTKVHSFAIFDTFFFFLTAKTFDFLNVRLVSQEVPTTKSIANSFKASGFSPADGDNFKSALADARPVA
VGRMITGTKTPKNGNREFPNLIHCFNKFAVMSVRNGDLYVPNSSESVPLEAFRITYMNKIDRAYIWYPYLLVFSPNVVEV
RLLTVKNFSKSLVQVITGRNIRLLTGASTHEESLEVKKDANPVNAIAKDRIIMAMDHPLRKTQLILEFTRNPDVKSDDLH
LVSDLTEFGC

GO term prediction

Biological Process

GO:0035023 regulation of Rho protein signal transduction

Molecular Function

GO:0005089 Rho guanyl-nucleotide exchange factor activity

Cellular Component

None predicted.