Protein

MCA_01808_1

Length
111 amino acids

Gene name: TOA2

Description: Transcription initiation factor IIA subunit 2

Browser: contigA:5504687-5505129-

RNA-seq: read pairs 1553, FPKM 171.3, percentile rank 86.4% (100% = highest expression)

Protein function

Annotation:TOA2Transcription initiation factor IIA subunit 2
KEGG:K03123TFIIA2 transcription initiation factor TFIIA small subunit
EGGNOG:0PPMKTOA2TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation (By similarity)
SGD closest match:S000001541TOA2Transcription initiation factor IIA subunit 2
CGD closest match:CAL0000177370TOA2Transcription initiation factor IIA subunit 2

Protein alignments

%idAln lengthE-value
MIA_02354_173.87%1111e-60MIA_02354_1
A0A060T2Z1_BLAAD73.64%1103e-58Transcription initiation factor IIA subunit 2 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A04928g PE=3 SV=1
A0A1E3PEY9_9ASCO74.77%1072e-56Transcription initiation factor IIA subunit 2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53127 PE=3 SV=1
A0A0J9X8I9_GEOCN68.27%1047e-50Transcription initiation factor IIA subunit 2 OS=Geotrichum candidum GN=BN980_GECA05s06445g PE=3 SV=1
UniRef50_H6BRR660.91%1107e-43Transcription initiation factor IIA subunit 2 n=42 Tax=Fungi TaxID=4751 RepID=H6BRR6_EXODN
Q6C0S4_YARLI55.45%1107e-43Transcription initiation factor IIA subunit 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F22136g PE=3 SV=1
A0A1E4TC03_9ASCO57.52%1131e-38Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_45736 PE=4 SV=1
Q5AMM1_CANAL47.29%1295e-35Transcription initiation factor IIA subunit 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TOA2 PE=3 SV=1
T2AG_YEAST44.63%1212e-33Transcription initiation factor IIA subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TOA2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0803

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 111

Detailed signature matches

  1. Family IPR003194
    Transcription initiation factor IIA, gamma subunit
    1. PIRSF009415 (TFIIA_...)
  2. Domain IPR009083
    Transcription factor IIA, helical
    1. SSF47396 (Transcrip...)
  3. Domain IPR015872
    Transcription initiation factor IIA, gamma subunit, N-terminal
    1. cd10145 (TFIIA_gamma_N)
    2. PF02268 (TFIIA_gamma_N)
    3. PD009224
  4. Domain IPR009088
    Transcription factor IIA, beta-barrel
    1. SSF50784 (Transcrip...)
    2. G3DSA:2.30.18.10
  5. Domain IPR015871
    Transcription initiation factor IIA, gamma subunit, C-terminal
    1. PF02751 (TFIIA_gamma_C)
    2. cd10014 (TFIIA_gamma_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.28...

Residue annotation

  1. TFIIA subunit inte...
  2. TFIIA subunit inte...
  3. TBP interface cd10...

Protein sequence

>MCA_01808_1
MSNSQYYELYRRSSIGTALTDALDHLISNSMIESQLAVKTLLRFDQVISEQLKEQVKSRCSLKGHLHTYRCCDDVWTFVV
KDVNFKMEENETVHAEKIKIVACNSRKTGEQ

GO term prediction

Biological Process

GO:0006367 transcription initiation from RNA polymerase II promoter

Molecular Function

None predicted.

Cellular Component

GO:0005672 transcription factor TFIIA complex