Protein

MCA_01653_1

Length
123 amino acids

Gene name: RPA12

Description: DNA-directed RNA polymerase I subunit RPA12

Browser: contigA:5081260-5081632-

RNA-seq: read pairs 340, FPKM 33.9, percentile rank 56.1% (100% = highest expression)

Protein function

Annotation:RPA12DNA-directed RNA polymerase I subunit RPA12
KEGG:K03000RPA12 DNA-directed RNA polymerase I subunit RPA12
EGGNOG:0PNWWRPA12DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SGD closest match:S000003824RPA12DNA-directed RNA polymerase I subunit RPA12
CGD closest match:CAL0000195650RPA12DNA-directed RNA polymerase subunit

Protein alignments

%idAln lengthE-value
MIA_03372_176.42%1232e-68MIA_03372_1
A0A0J9XFC5_GEOCN72.58%1247e-63DNA-directed RNA polymerase subunit OS=Geotrichum candidum GN=BN980_GECA13s02694g PE=3 SV=1
A0A1D8PHV8_CANAL69.92%1239e-60DNA-directed RNA polymerase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPA12 PE=3 SV=1
A0A1E3PFU3_9ASCO66.67%1236e-58DNA-directed RNA polymerase subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83810 PE=3 SV=1
RPA12_YEAST67.20%1252e-57DNA-directed RNA polymerase I subunit RPA12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPA12 PE=1 SV=1
UniRef50_P3252967.20%1255e-54DNA-directed RNA polymerase I subunit RPA12 n=57 Tax=saccharomyceta TaxID=716545 RepID=RPA12_YEAST
Q6CHJ6_YARLI66.13%1246e-57DNA-directed RNA polymerase subunit OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A08151g PE=3 SV=1
A0A060T5E3_BLAAD66.94%1242e-56DNA-directed RNA polymerase subunit OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11484g PE=3 SV=1
A0A1E4THJ8_9ASCO57.14%1263e-46DNA-directed RNA polymerase subunit OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_121657 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0235

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 123

Detailed signature matches

  1. Family IPR012164
    DNA-directed RNA polymerase subunit/transcription factor S
    1. PIRSF005586 (RNApol...)
  2. Domain IPR001529
    DNA-directed RNA polymerase, M/15kDa subunit
    1. PF02150 (RNA_POL_M_...)
    2. SM00661 (rpol9cneu)
  3. Domain IPR001222
    Zinc finger, TFIIS-type
    1. PS51133 (ZF_TFIIS_2)
    2. PF01096 (TFIIS_C)
    3. PS00466 (ZF_TFIIS_1)
    4. SM00440 (Cys4_2)
  4. Domain IPR034004
    Pol I subunit A12, C-terminal zinc ribbon
    1. cd10507 (Zn-ribbon_...)
  5. SITE IPR019761
    DNA-directed RNA polymerase M, 15kDa subunit, conserved site
    1. PS01030 (RNA_POL_M_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.20.25.10
  2. G3DSA:2.20.28.10
  3. G3DSA:3.30.60.20
  4. SSF57783 (Zinc beta...)

Residue annotation

  1. Zn binding site cd...

Protein sequence

>MCA_01653_1
MAAVGSLIFCTKCGNLLDNALGEKRLKCSDCSMTYNASQFSDLKVVTSSSETAFPSSLRLKRSVVKTQLSKEHLEEGAII
KEKCPECGNEEMQYHTLQLRSADEGATVFYTCTKCNYRFRTNN

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated
GO:0006379 mRNA cleavage

Molecular Function

GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.