Protein
MCA_01622_1
Length
548 amino acids
Gene name: DHH1
Description: ATP-dependent RNA helicase DHH1
Browser: contigA:4999282-5000929-
RNA-seq: read pairs 2912, FPKM 65.5, percentile rank 71.1% (100% = highest expression)
Protein function
Annotation: | DHH1 | ATP-dependent RNA helicase DHH1 | |
---|---|---|---|
KEGG: | K12614 | DDX6 | ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13] |
EGGNOG: | 0PGHM | DHH1 | ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1 S DNA- damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity) |
SGD closest match: | S000002319 | DHH1 | ATP-dependent RNA helicase DHH1 |
CGD closest match: | CAL0000182112 | DHH1 | ATP-dependent RNA helicase DHH1 |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_00253_1 | 94.16% | 428 | 0.0 | MIA_00253_1 |
A0A060T2K6_BLAAD | 90.02% | 421 | 0.0 | ARAD1C26004p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C26004g PE=3 SV=1 |
A0A0J9XIF7_GEOCN | 89.81% | 422 | 0.0 | Similar to Saccharomyces cerevisiae YDL160C DHH1 Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping OS=Geotrichum candidum GN=BN980_GECA19s00395g PE=3 SV=1 |
A0A167CT65_9ASCO | 89.00% | 418 | 0.0 | DExD/H-box ATP-dependent RNA helicase DHH1 OS=Sugiyamaella lignohabitans GN=DHH1 PE=3 SV=1 |
A0A1E3PR31_9ASCO | 85.05% | 428 | 0.0 | Putative DEAD-box RNA helicase Dhh1/Vad1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48421 PE=3 SV=1 |
DHH1_YARLI | 86.60% | 418 | 0.0 | ATP-dependent RNA helicase DHH1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DHH1 PE=3 SV=1 |
UniRef50_A2QY39 | 78.97% | 428 | 0.0 | ATP-dependent RNA helicase dhh1 n=5 Tax=Eurotiales TaxID=5042 RepID=DHH1_ASPNC |
DHH1_CANAL | 80.43% | 419 | 0.0 | ATP-dependent RNA helicase DHH1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DHH1 PE=3 SV=1 |
DHH1_YEAST | 79.57% | 416 | 0.0 | ATP-dependent RNA helicase DHH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DHH1 PE=1 SV=1 |
A0A1E4TCP8_9ASCO | 76.64% | 411 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_140291 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0113
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
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Domain
1
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100
150
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548
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd00079 (HELICc)
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cd00268 (DEADc)
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mobidb-lite (disord...)
Residue annotation
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ATP binding site c...
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Mg++ binding site ...
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motif III cd00268
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nucleotide binding...
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ATP-binding site c...
Protein sequence
>MCA_01622_1 MSSGKQESDWKSSLNIPTKDTRPQTEDVTNIKGNGFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPIALAGRDILARAKN GTGKTAAFVIPALQQINPKINKIQALILVPTRELALQTSQVCKTLGKHLGIQVMATTGGTNLKDDILRLNETVHVLVGTP GRVLDFAGKSVIDFSECPMFIMDEADKLLSPEFSPVVEQLLGYFPPSRQILLFSATFPLVVKSFMDKHLNKPYEINLMDE LTLRGITQYYAFVEEKQKLHCLNTLFSKLQINQSIIFCNSTNRVELLARKITELGYSCYFSHAKMLQSHRNRVFHEFRNG NCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRFGHLGLAINLINWNDRYSLYKIEQELGTEIKPIPAH IDTSLYVADAAENIPKPFPIAELPRDSANRNQRFNNNNNNNNNNNYPNGNRPQQQIEQGPSGNGYQMPMPQGQPYNQMPP QNYMSQQPQQPQQPQQYPMNQQNMYNSNGKPGMGNMNGNPQAQPNYPPQPSFMQGYPPQQPAYYNQQR
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding
Cellular Component
None predicted.