Protein

MCA_01490_1

Length
1,002 amino acids

Browser: contigA:4616767-4619898+

RNA-seq: read pairs 1727, FPKM 21.3, percentile rank 42.9% (100% = highest expression)

Protein function

KEGG:K12852EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component
EGGNOG:0PHCWPGUG_01462u5 small nuclear ribonucleoprotein component
SGD closest match:S000001656SNU114Pre-mRNA-splicing factor SNU114
CGD closest match:CAL0000191291SNU114U5 snRNP GTPase

Protein alignments

%idAln lengthE-value
MIA_00356_167.17%9900.0MIA_00356_1
A0A0J9XAK3_GEOCN58.41%9930.0Similar to Saccharomyces cerevisiae YKL173W SNU114 GTPase component of U5 snRNP involved in mRNA splicing via spliceosome OS=Geotrichum candidum GN=BN980_GECA07s02419g PE=4 SV=1
A0A060T6H6_BLAAD50.50%9960.0ARAD1C20130p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20130g PE=4 SV=1
A0A1E3PH89_9ASCO49.56%10170.0p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52639 PE=4 SV=1
UniRef50_A0A1E3PH8949.56%10170.0p-loop containing nucleoside triphosphate hydrolase protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PH89_9ASCO
A0A167F681_9ASCO52.62%9350.0U5 snRNP GTPase SNU114 OS=Sugiyamaella lignohabitans GN=SNU114 PE=4 SV=1
A0A1E4TKW9_9ASCO43.01%9300.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_86108 PE=4 SV=1
Q6CGB0_YARLI42.79%10050.0YALI0A20768p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A20768g PE=4 SV=1
SN114_YEAST33.37%10409e-180Pre-mRNA-splicing factor SNU114 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SNU114 PE=1 SV=1
A0A1D8PH71_CANAL33.79%10862e-164U5 snRNP GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SNU114 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0348

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1002

Detailed signature matches

  1. Domain IPR031950
    116kDa U5 small nuclear ribonucleoprotein component, N-terminal
    1. PF16004 (EFTUD2)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
  4. Domain IPR000795
    Transcription factor, GTP-binding domain
    1. PS51722 (G_TR_2)
    2. PF00009 (GTP_EFTU)
    3. PR00315 (ELONGATNFCT)
  5. Domain IPR009000
    Translation protein, beta-barrel domain
    1. SSF50447 (Translati...)
  6. Domain IPR035647
    EF-G domain III/V-like
    1. SSF54980 (EF-G C-te...)
  7. Domain IPR020568
    Ribosomal protein S5 domain 2-type fold
    1. SSF54211 (Ribosomal...)
  8. Domain IPR014721
    Ribosomal protein S5 domain 2-type fold, subgroup
    1. G3DSA:3.30.23...
  9. Domain IPR005517
    Translation elongation factor EFG/EF2, domain IV
    1. PF03764 (EFG_IV)
    2. SM00889 (EFG_IV_2)
  10. Domain IPR000640
    Elongation factor EFG, domain V-like
    1. PF00679 (EFG_C)
    2. SM00838 (EFG_C_a)
  11. SITE IPR031157
    Tr-type G domain, conserved site
    1. PS00301 (G_TR_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.30.10
  2. G3DSA:3.30.70...
  3. G3DSA:3.30.70...
  4. G3DSA:3.40.50...
  5. G3DSA:3.90.14...
  6. cd01683 (EF2_IV_snRNP)
  7. cd04090 (EF2_II_snRNP)
  8. cd04167 (Snu114p)
  9. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd04167
  2. putative GEF inter...
  3. GTP/Mg2+ binding s...
  4. Switch I region cd...
  5. G2 box cd04167
  6. G3 box cd04167
  7. Switch II region c...
  8. G4 box cd04167
  9. G5 box cd04167

Protein sequence

>MCA_01490_1
MDEDLYDEFGNYIGPDSDEEANSPVDVENADDLAKQYIDNDDDEPEDDGVENHETNDSMAIVLHEDKQYYPSAQEIYGEG
VETMVQERDAQDLSEPIIAPVKVNTHMAEERDLPELTYSREWQASLMQLPDHIRNIALVGQLHHGKTSFLDMLINETHIF
PPREGRKQDVQQRYTDTHILEQKRGITIKSSPISLVLKNTKGKSFLFNIMDTPGHSNFLDEVSIAARYADGFVLVVDVLE
GLLTGTKHIIDYAIKYNIPLVLVLNKIDRLIVELKLPPTEALYKIQYTIDQVNSYINSKCPFKNKRYLPFSPELNNVVFS
SSTCNFIFTLKSFALKYQQEYSADLDVEAFAKRLWGNIFYNKESRKFTRKPVETGAKRTFEHFILIPLYKIFTHVLEEEK
DSLSGTLAKLNISLKNSTYKLDVKPLLQTVFKLFFEDSSALVDSILEHFPSPTEGSQRYLERFYSGSPEGIEYKAMLNGD
PKGPLVVHVAKLYNRTDIESGRFYALGRVMSGTLWKNANLSVLGETYTNFDFEDLQECVASELWNYQSRYKVPIDGVTPG
NWVLIQGVDSSITKTGTIYQTNELDEEEMHIFKPIKYLGEPVLKVAVEPYNPSELPKMLDGLLSIAKSYGAVQTKAEESG
EHVIIGTGEMYMDCVLHDLRTVYANMHVKVSDPVAKFAETCLETSAIRAYTETPNKHNKITIIAEPLSEEICDDIENEVV
TLGGPIDKYGVSGRSGEKWTPKKVAQFFQEKYGWDIMSARSIWSFGPEISKPNILQDDTLSEEVDKLAMKSIKEAVKQGF
QWAIRDGPLCDEPIRNVRFKIIEAELSKIPSQRNSSQIISTVRRACYSAMLLASPRLMEPLYQFEIIVPFNHIAAVKTIV
QTQRRGHIDTDTPLLGTPLRILIGDVPVIDSAGFETDIRIITKGAGFISSLQFYKWSIVPGDPLDKDQDGAVRPLEVASP
QSMAREFVIKTRKRKGLSDQPTVTKYLDESLLESLKDSGLLD

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.