Protein

MCA_01292_1

Length
640 amino acids

Gene name: CLP1

Description: mRNA cleavage and polyadenylation factor CLP1

Browser: contigA:4058000-4060066+

RNA-seq: read pairs 1057, FPKM 20.4, percentile rank 42.0% (100% = highest expression)

Protein function

Annotation:CLP1mRNA cleavage and polyadenylation factor CLP1
KEGG:K14399CLP1 polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
EGGNOG:0PK9ECLP1Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation (By similarity)
SGD closest match:S000005776CLP1mRNA cleavage and polyadenylation factor CLP1
CGD closest match:CAL0000199618CLP1mRNA cleavage and polyadenylation factor CLP1

Protein alignments

%idAln lengthE-value
MIA_01871_147.80%5005e-141MIA_01871_1
A0A0J9XFP0_GEOCN38.26%4606e-91mRNA cleavage and polyadenylation factor CLP1 OS=Geotrichum candidum GN=CLP1 PE=3 SV=1
UniRef50_A0A0J9XFP038.26%4601e-87mRNA cleavage and polyadenylation factor CLP1 n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XFP0_GEOCN
A0A060T9K1_BLAAD38.51%4572e-90mRNA cleavage and polyadenylation factor CLP1 OS=Blastobotrys adeninivorans GN=CLP1 PE=3 SV=1
A0A167CWD1_9ASCO45.12%2974e-81Clp1p OS=Sugiyamaella lignohabitans GN=CLP1 PE=4 SV=1
A0A1E3PP20_9ASCO42.81%3136e-70mRNA cleavage and polyadenylation factor CLP1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=CLP1 PE=3 SV=1
CLP1_YARLI30.70%4562e-51mRNA cleavage and polyadenylation factor CLP1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CLP1 PE=3 SV=1
CLP1_CANAL29.36%4535e-49mRNA cleavage and polyadenylation factor CLP1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CLP1 PE=3 SV=1
A0A1E4TI75_9ASCO31.79%3242e-42Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_19614 PE=3 SV=1
CLP1_YEAST36.63%2434e-40mRNA cleavage and polyadenylation factor CLP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLP1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0098

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 640

Detailed signature matches

  1. Family IPR028606
    Polyribonucleotide 5-hydroxyl-kinase Clp1
    1. MF_03035 (Clp1)
  2. Domain IPR032324
    Clp1, N-terminal beta-sandwich domain
    1. PF16573 (CLP1_N)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR032319
    Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain
    1. PF16575 (CLP1_P)
  5. Domain IPR010655
    Pre-mRNA cleavage complex subunit Clp1
    1. PF06807 (Clp1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. mobidb-lite (disord...)

Protein sequence

>MCA_01292_1
MSVNIPGFNSFTGETSGKSDTVKITVQPYSEWRFEIPARCKYQIKLLKGTAEIFGTELAIGPEYTFTNYKAAIYTWHGCT
LEVTNITKNTIGLQQQGLRTSYAKSSGGNNSDLLPGGGFEGSTVEGQSIDLASSDVMTGDSSFKKQQNEISEYISEESQM
PFYANLHFAFENARQLSEQREDMDNDENMSGDETTSNNHPPNANNKQKASKVLEHPPRVLVIGPQDSGKSSLCKILVSYD
VKRGRTPMFVNLDTVESVFCAPGSVSAAVISDILDVEQGWGNSPITGPTLLHPKQPLVRFFGLDNPMKNPEYYCEIMSLM
AKSVRSRLEDDYNARSSGIYIDTPAALVSPQNKQQGYAIIEKIIQEFDINVLLVVGNEKLYSDMKKTYESNNSKIPLTAV
VKVPKSGGAVDRDIEFMTALQSSLINEYFYGTPKQPLSPYTVTINYSHVKMFRIAERKISASETESSSATSAVTTTTASN
SVSSSKDTSLALPETSTESETIDKEKSSEEQQSSLAADTTTTDTTENEEKTVVVSEDAPTTETETETEKTSSSSSRSNDE
KSEGQYLISLEPSSIVENGLLAVLAANPEDPIEEIAKANVLGYVHIVEADDNRKRMRILMPVYGRLPNCPLVLGDFRYYE

GO term prediction

Biological Process

GO:0031124 mRNA 3'-end processing

Molecular Function

None predicted.

Cellular Component

GO:0005849 mRNA cleavage factor complex