Protein
MCA_01134_1
Length
662 amino acids
Gene name: ACS1
Description: Acetyl-coenzyme A synthetase
Browser: contigA:3613229-3615290+
RNA-seq: read pairs 2934, FPKM 54.7, percentile rank 67.2% (100% = highest expression)
Protein function
| Annotation: | ACS1 | Acetyl-coenzyme A synthetase | |
|---|---|---|---|
| KEGG: | K01895 | ACSS | acetyl-CoA synthetase [EC:6.2.1.1] |
| EGGNOG: | 0PGXP | ACS1 | Acetate-CoA ligase |
| SGD closest match: | S000004143 | ACS2 | Acetyl-coenzyme A synthetase 2 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00296_1 | 89.50% | 657 | 0.0 | MIA_00296_1 |
| A0A0J9XH17_GEOCN | 86.97% | 660 | 0.0 | Acetyl-coenzyme A synthetase OS=Geotrichum candidum GN=BN980_GECA16s00208g PE=3 SV=1 |
| A0A060T8N5_BLAAD | 78.25% | 662 | 0.0 | Acetyl-coenzyme A synthetase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D12826g PE=3 SV=1 |
| A0A1E3PPW9_9ASCO | 75.75% | 668 | 0.0 | Acetyl-coenzyme A synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81952 PE=3 SV=1 |
| Q6C2Q5_YARLI | 77.93% | 648 | 0.0 | Acetyl-coenzyme A synthetase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F05962g PE=3 SV=1 |
| A0A1E4TAC1_9ASCO | 70.95% | 661 | 0.0 | Acetyl-coenzyme A synthetase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3299 PE=3 SV=1 |
| UniRef50_G0RZW2 | 70.05% | 661 | 0.0 | Acetyl-coenzyme A synthetase-like protein n=1 Tax=Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) TaxID=759272 RepID=G0RZW2_CHATD |
| A0A167BYL8_9ASCO | 71.88% | 640 | 0.0 | Acetyl-coenzyme A synthetase OS=Sugiyamaella lignohabitans GN=ACS2 PE=3 SV=1 |
| Q59XW4_CANAL | 68.29% | 656 | 0.0 | Acetyl-coenzyme A synthetase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ACS1 PE=3 SV=1 |
| ACS2_YEAST | 63.38% | 669 | 0.0 | Acetyl-coenzyme A synthetase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ACS2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0363
Protein family membership
- Acetate-CoA ligase (IPR011904)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
662
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
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SSF56801 (Acetyl-Co...)
Residue annotation
-
CoA binding site c...
-
active site cd05966
-
acyl-activating en...
-
acetate binding si...
-
AMP binding site c...
Protein sequence
>MCA_01134_1 MSAPVVAESHNVQKYAPPKEFRDNHPTKPHLDDHGHYEEMYQESIKNPDKFFGNIGRELLSWSKDFKTVRNGGFKDGDIS WFLEGELNASYNCVDRHAFKNPDKVAIIYEADEPGEGRKVTYGELLQEVSRVAAVLTSFGVKKGDTVAVYLPMIPEALIT LLAITRIGAVHSVIFAGFSSGSLKDRILDADSRVVITADESKRGGRVIETKKIVDEALKSCPNVKHTLVFKRTGNENINW NKDRDYWWHEEVAKHRPYFPPVNVNSEDPIFLLYTSGSTGSPKGVAHSTAGYLLGAATTTKYVFDLHEDDILFTAGDVGW ITGHTYVCYGPLLLGATTVVFEGTPAYPNFSRLWDIVDEHKISHFYVAPTALRLLKRAGTQWINHDLSSLRTLGSVGEPI APDVWEWYNENIGKGKAHICDTYWQTETGSHIISPMAGVTHTKPGSASFPVFGIDPVIIDPVTGKELEGNDVEGVLAIRN PWPSMARTVWNSHKRYMETYLLPYPGYYFTGDGAGRDHEGYYWIRGRVDDVVNVSGHRLSTAEIEAALIEHPSVAESAVV GISDDLTGQAVNAFVALKTKPSDVAATKKELILQVRKSIGPFAAPKNVLIVEDLPKTRSGKIMRRILRKVLSGEEDQLGD ISTLANPEAVDNIIQVCKAERK
GO term prediction
Biological Process
GO:0008152 metabolic process
GO:0019427 acetyl-CoA biosynthetic process from acetate
Molecular Function
GO:0003824 catalytic activity
GO:0003987 acetate-CoA ligase activity
GO:0016208 AMP binding
Cellular Component
None predicted.