Protein
MCA_00942_1
Length
195 amino acids
Gene name: PRE1
Description: Proteasome subunit beta type-4
Browser: contigA:2959726-2960509+
RNA-seq: read pairs 4127, FPKM 260.2, percentile rank 90.8% (100% = highest expression)
Protein function
| Annotation: | PRE1 | Proteasome subunit beta type-4 | |
|---|---|---|---|
| KEGG: | K02734 | PSMB2 | 20S proteasome subunit beta 4 [EC:3.4.25.1] |
| EGGNOG: | 0PHXK | PRE1 | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity) |
| SGD closest match: | S000000814 | PRE1 | Proteasome subunit beta type-4 |
| CGD closest match: | CAL0000196012 | PRE1 | Proteasome core particle subunit beta 4 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04370_1 | 79.49% | 195 | 5e-120 | MIA_04370_1 |
| A0A0J9XFP4_GEOCN | 76.41% | 195 | 3e-112 | Similar to Saccharomyces cerevisiae YER012W PRE1 Beta 4 subunit of the 20S proteasome OS=Geotrichum candidum GN=BN980_GECA13s03112g PE=4 SV=1 |
| A0A167D5W4_9ASCO | 69.39% | 196 | 5e-103 | Proteasome core particle subunit beta 4 OS=Sugiyamaella lignohabitans GN=PRE1 PE=4 SV=1 |
| A0A1E3PJZ5_9ASCO | 69.23% | 195 | 9e-102 | Proteasome component C11 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46398 PE=4 SV=1 |
| A0A060TB60_BLAAD | 65.13% | 195 | 4e-97 | ARAD1D32384p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32384g PE=4 SV=1 |
| PSB4_YEAST | 62.05% | 195 | 4e-93 | Proteasome subunit beta type-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRE1 PE=1 SV=2 |
| UniRef50_P22141 | 62.05% | 195 | 9e-90 | Proteasome subunit beta type-4 n=348 Tax=Eukaryota TaxID=2759 RepID=PSB4_YEAST |
| Q5AJZ5_CANAL | 61.86% | 194 | 1e-89 | Proteasome core particle subunit beta 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRE1 PE=4 SV=1 |
| Q6CF05_YARLI | 62.11% | 190 | 4e-80 | YALI0B11374p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11374g PE=4 SV=1 |
| A0A1E4TC31_9ASCO | 55.21% | 192 | 9e-76 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13934 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0297
Protein family membership
- Proteasome, subunit alpha/beta (IPR001353)
- Proteasome B-type subunit (IPR023333)
- Proteasome subunit beta 2 (IPR035206)
- Proteasome B-type subunit (IPR023333)
Domains and repeats
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Domain
1
20
40
60
80
100
120
140
160
180
195
Detailed signature matches
Protein sequence
>MCA_00942_1 MDVLLGITTKDSVIIATSKAAMRGISVLKSDDDKTRDLTSTTTMAFSGEAGDTIQFAEYMMANIQLYGMRNGYEMSSTAI ASFIRNELANALRSRKPYQVNLLVGSYDTKKQKPVLNWIDYLAACVSLPYAAHGHASYYVLSLLDRHHRPDMTLEEGLEL TKLCIEEVKRRIPLDFKGIQIKIVDKDGIRLSEDL
GO term prediction
Biological Process
GO:0051603 proteolysis involved in cellular protein catabolic process
Molecular Function
GO:0004298 threonine-type endopeptidase activity
Cellular Component
GO:0005839 proteasome core complex