Protein
MCA_00778_1
Length
397 amino acids
Gene name: BNA7B
Description: Kynurenine formamidase
Browser: contigA:2426604-2427798-
RNA-seq: read pairs 859, FPKM 26.7, percentile rank 49.4% (100% = highest expression)
Protein function
| Annotation: | BNA7B | Kynurenine formamidase | |
|---|---|---|---|
| EGGNOG: | 0PPMY | BNA7 | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites (By similarity) |
| CGD closest match: | CAL0000192193 | BNA7 | Kynurenine formamidase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01009_1 | 56.80% | 338 | 1e-119 | MIA_01009_1 |
| A0A0J9X963_GEOCN | 51.49% | 336 | 8e-108 | Similar to Saccharomyces cerevisiae YDR428C BNA7 Formylkynurenine formamidase, involved in the de novo biosynthesis of NAD from tryptophan via kynurenine OS=Geotrichum candidum GN=BN980_GECA06s03288g PE=4 SV=1 |
| Q6CCT4_YARLI | 44.41% | 340 | 8e-90 | YALI0C06732p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C06732g PE=4 SV=1 |
| UniRef50_Q6CCT4 | 44.41% | 340 | 2e-86 | YALI0C06732p n=4 Tax=Saccharomycetales TaxID=4892 RepID=Q6CCT4_YARLI |
| A0A1E3PFT8_9ASCO | 46.15% | 338 | 8e-88 | Alpha/beta-hydrolase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52570 PE=4 SV=1 |
| A0A167D7X6_9ASCO | 24.87% | 193 | 2e-14 | Kynurenine formamidase OS=Sugiyamaella lignohabitans GN=BNA7 PE=3 SV=1 |
| KFA_CANAL | 26.59% | 173 | 5e-14 | Kynurenine formamidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BNA7 PE=3 SV=1 |
| A0A060TDW1_BLAAD | 26.37% | 182 | 8e-14 | ARAD1D03190p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D03190g PE=4 SV=1 |
| A0A1E4TGT7_9ASCO | 29.21% | 178 | 2e-13 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26848 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.4431
Predicted cleavage: 33
Protein family membership
None predicted.
Domains and repeats
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Domain
1
50
100
150
200
250
300
350
397
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
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mobidb-lite (disord...)
Protein sequence
>MCA_00778_1 MPLIFDTANQPSNPNSRRNSLTHFFTSSNNRNNTSSSNNSNNILFDDSGSSIVSYLPRPKRPKPITLPYQSSPNPFHTLD LYLPASGLAPDTPWFIFLHGGYWQDASQSKEVGAAILTRLPTHWAGASIDYRLSPEVGYPGHLLDVKKAIKFLKQAYGLS SAVIMAHGAGACIAYQYLFSELQSCNEYNDDNDNNNASNPYGLRSVQQSNNGRFNNSNSNSNNANKNKSWIKHVITSGGV YDLVQLARDSPYYNKYIADAYGDDLEHWYELSPQNFEWASLNSSCNNDSDSLQTQESSNNNNNNDTTDSNNDNETTYNGP RITLVHSKFDLIVPLQQSLKFDSMLTEAGYKVSLRLLNVDGHDSVLETAELALLALEVCQTLDDEIEKQHTDSANLA
GO term prediction
Biological Process
GO:0008152 metabolic process
Molecular Function
GO:0016787 hydrolase activity
Cellular Component
None predicted.