Protein

MCA_00757_1

Length
392 amino acids

Gene name: RFC2

Description: Replication factor C subunit 2; DNA binding protein and ATPase

Browser: contigA:2369042-2370362+

RNA-seq: read pairs 599, FPKM 18.8, percentile rank 39.9% (100% = highest expression)

Protein function

Annotation:RFC2Replication factor C subunit 2; DNA binding protein and ATPase
KEGG:K10755RFC2_4 replication factor C subunit 2/4
EGGNOG:0PH5YFG01208.1replication factor C subunit
SGD closest match:S000003829RFC2Replication factor C subunit 2
CGD closest match:CAL0000195843RFC2Replication factor C subunit 2

Protein alignments

%idAln lengthE-value
A0A0J9X3N0_GEOCN62.47%3979e-177Similar to saccharomyces cerevisiae YJR068W RFC2 Subunit of heteropentameric Replication factor C (RF-C) OS=Geotrichum candidum GN=BN980_GECA02s01011g PE=4 SV=1
A0A1E3PFE3_9ASCO62.84%3662e-162p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28048 PE=4 SV=1
A0A060TE21_BLAAD59.24%3682e-154ARAD1D12144p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D12144g PE=4 SV=1
UniRef50_A0A0U1LYT957.11%3873e-146Endo-chitosanase n=3 Tax=Eurotiomycetidae TaxID=451871 RepID=A0A0U1LYT9_TALIS
MIA_05624_164.95%3315e-149MIA_05624_1
Q6C6B9_YARLI55.77%3647e-141YALI0E10747p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E10747g PE=4 SV=1
RFC2_YEAST56.75%3635e-141Replication factor C subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RFC2 PE=1 SV=1
A0A1D8PQP2_CANAL55.56%3695e-141Replication factor C subunit 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RFC2 PE=4 SV=1
A0A167FC67_9ASCO59.23%3366e-136Replication factor C subunit 2 OS=Sugiyamaella lignohabitans GN=RFC2 PE=4 SV=1
A0A1E4TLQ1_9ASCO53.60%3476e-131Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_90613 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1534

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 392

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  3. Domain IPR003959
    ATPase, AAA-type, core
    1. PF00004 (AAA)
  4. Domain IPR008921
    DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
    1. SSF48019 (post-AAA+...)
  5. Domain IPR013748
    Replication factor C, C-terminal
    1. PF08542 (Rep_fac_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.8.60
  2. G3DSA:1.20.27...
  3. G3DSA:3.40.50...
  4. cd00009 (AAA)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...

Protein sequence

>MCA_00757_1
MSFFDMRARRDALAKKKSSDSSTKDNIPWVEKYRPKQLNQVTAQDHVVTVIKRTLESQNLPHMLFYGPPGTGKTSTILAL
AKELYGPTLAKSRVLELNASDERGISIVREKVKTFARMSISQASGADRKDHPCPPYKIVILDEADSMTSDAQSALRRTME
LYSKTTRFCLICNYVTRIIDPIASRCAKFRFKPLDETNAIGRLEYIATQEELNYEPGVLEALLKASEGDLRKAITFLQSA
ARLTKAPKVSLTENDTQNDDEDVVMTEAEVPELENKIITIKSIQEIAGVIPDSIIEGLVESCKSKAYPKKSFGEDCFDNI
MAAVQEVILDGWSATQILTQLHDRLMFDDLITAKQKNEISWQLSESDKRLADGTDEHLEILNTLTKFAQVIY

GO term prediction

Biological Process

GO:0006260 DNA replication

Molecular Function

GO:0003677 DNA binding
GO:0005524 ATP binding

Cellular Component

None predicted.