Protein
MCA_00741_1
Length
1,473 amino acids
Gene name: VPS15
Description: Serine/threonine-protein kinase Vps15; S. cerevisiae homologue is involved in vacuolar protein sorting
Browser: contigA:2311543-2316112-
RNA-seq: read pairs 940, FPKM 7.9, percentile rank 22.1% (100% = highest expression)
Protein function
Annotation: | VPS15 | Serine/threonine-protein kinase Vps15; S. cerevisiae homologue is involved in vacuolar protein sorting | |
---|---|---|---|
KEGG: | K08333 | PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1] |
EGGNOG: | 0PI6P | VPS15 | protein kinase (VPS15) |
SGD closest match: | S000000301 | VPS15 | Serine/threonine-protein kinase VPS15 |
CGD closest match: | CAL0000193001 | VPS15 | Ubiquitin-binding serine/threonine protein kinase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_05458_1 | 59.05% | 1487 | 0.0 | MIA_05458_1 |
A0A0J9X9Y0_GEOCN | 51.17% | 1493 | 0.0 | Similar to Saccharomyces cerevisiae YBR097W VPS15 Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting OS=Geotrichum candidum GN=BN980_GECA06s03354g PE=4 SV=1 |
UniRef50_A0A0J9X9Y0 | 51.17% | 1493 | 0.0 | Similar to Saccharomyces cerevisiae YBR097W VPS15 Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9Y0_GEOCN |
A0A060T6G4_BLAAD | 39.95% | 1517 | 0.0 | ARAD1B11946p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B11946g PE=4 SV=1 |
A0A1E4TGZ5_9ASCO | 34.79% | 1529 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2665 PE=4 SV=1 |
A0A167CVY0_9ASCO | 36.05% | 1373 | 0.0 | Ubiquitin-binding serine/threonine protein kinase VPS15 OS=Sugiyamaella lignohabitans GN=VPS15 PE=4 SV=1 |
Q6C3L7_YARLI | 42.00% | 869 | 0.0 | YALI0E33774p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E33774g PE=4 SV=1 |
VPS15_YEAST | 31.81% | 1377 | 0.0 | Serine/threonine-protein kinase VPS15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS15 PE=1 SV=4 |
A0A1D8PPK3_CANAL | 36.41% | 909 | 9e-173 | Ubiquitin-binding serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VPS15 PE=4 SV=1 |
A0A1E3PNT5_9ASCO | 31.67% | 944 | 2e-146 | WD40 repeat-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81694 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1897
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
-
Repeat
1
200
400
600
800
1000
1200
1473
Detailed signature matches
no IPR
Unintegrated signatures
-
-
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cd13980 (STKc_Vps15)
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mobidb-lite (disord...)
Residue annotation
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ATP binding site c...
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active site cd13980
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polypeptide substr...
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activation loop (A...
Protein sequence
>MCA_00741_1 MGNQLSATTPTSTTVAIDAYISELQTVQYDRNLGNARFLKTVKGVSEGSLVVVKVFIKPGHDVFLSDIDREMFRQRNILL NIDNSLPYSRFLETDRAGYLVRQYIKTNLYDRISTRPFLEPIEKLWIVFQLLTCLNKCHQASVYHGDIKSENILVTSWNW VYLTDFASFKPAFIPETDPSQFYFFFDSSQRRSCYLAPERFHSAEEIIHGGITPAMDIFSLGCVIAELFLEGTHIFNLAQ LFKYRKGDYIPSLEGIENEYVKQMITQMISLDPKDRKTASHYLTEWKHKLFPDYFYDFLYDFVANVSMTNQYDNSGKPFK PNLFLDNRMSYIYNNFTDITTHLGFRVTLEDTTAAILDNNRHMLPNFLELPGTRKVIEKQDLAMDITRDDGALIVLSIVL STIRNVSNSSLKIKGCDLIIALGEMINDDAKLDRCLPYFLTLLDDPSELVQASAIRNMIKLLGMVTTITPLNGEIFLEYI FPKLDTILRSNPKKSIFVRVMYASCFPSLAQIALRFLEMSQILKTSGMFDSYDPETENGSRFGIIPFDLNRQGLIEKFEE HTIALLSDEDTSVKKAILREVVPLCLFFGKQKTNDIVLSHILTYLNDPDYSLKTQFFDSIIGLGPFIGPVALEEYIQPLT LQALNDTEEFVIAKTFEAYKAFAEFGLIREKSIWSLLEISVRYTVHPNLWIRNAAVSFVSASTTWMSASEIYCMLYPILR PYLENDITEFSQANITLHIKQPLSRSFFNWAVTWASKAQKSIFWKSAAKKAETDKYSSDQTTTIYLNSTDKILLSSEDQI WVGRLKKKGGKEEDLWKIKALEDHIYKLAAAIVSTQKPLLNDNTLIKGDRGKSQDLINNFTTVESLGIKPDRYKFTTGDY DWDNEDDPSRPISKESSSDALLNLDGMKSALKETVVHVNQASKNDSIASNLLGDHFGDQNGATAEPSVAVIGTSTTQAYG TVEQPFSTIQKPPSAPSPDFSSNLQEQQINVYVSKFLSAQNVIHGKTEPAEFGPQVIPVLYAENFHSLSVYGPTSNWRPS GVLASRFVEHTAAVNKIVPSPDHSFFLSCSDDGSIKIWDCARLEKNVINRSIQTISYGSETKVKFICFMVNSYTIAASLS TGKIAFIRVDVSLLKNASRVRFKKFVPLKTFELQKGEYATWMKHVKTNRSSVLIITTTKSRIIGINVSTLKEDFSFSCPL NHGVPTCFIVDYRKCWMLVGTQQGVLDLYDLRFNVLAKSWTFENAAPIYSLDFLPRSKERKFCMLGGTSKNEVTIWDVTN MTCHGVYTNSASIDQSKNYSAINFEELTTEKHKSLVSKQFDIAPKSSDIFCMAVGIDSKANKDDEPHIHILSGGADRKVR FWDLNSVNMSTIVSGLTTNAKPPTFFQAYNNFSIKVVAEKSTVGEPQDSSDISSNTGTKITRPLKPTRTAVIAAEQQDLA RNHSASITDIAILHRPYQMVISADITGVIRVYI
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
Cellular Component
None predicted.