Protein
MCA_00683_1
Length
270 amino acids
Gene name: UTR4
Description: Enolase-phosphatase E1
Browser: contigA:2124750-2125563+
RNA-seq: read pairs 1389, FPKM 63.3, percentile rank 70.4% (100% = highest expression)
Protein function
| Annotation: | UTR4 | Enolase-phosphatase E1 | |
|---|---|---|---|
| KEGG: | K09880 | mtnC | enolase-phosphatase E1 [EC:3.1.3.77] |
| EGGNOG: | 0PN8S | UTR4 | Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity) |
| SGD closest match: | S000000764 | UTR4 | Enolase-phosphatase E1 |
| CGD closest match: | CAL0000179480 | UTR4 | Enolase-phosphatase E1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01730_1 | 52.38% | 273 | 3e-75 | MIA_01730_1 |
| A0A0J9X9N7_GEOCN | 51.29% | 271 | 1e-71 | Similar to Saccharomyces cerevisiae YEL038W UTR4 Protein with sequence similarity to 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatases OS=Geotrichum candidum GN=BN980_GECA06s05125g PE=4 SV=1 |
| A0A060T2Y0_BLAAD | 43.02% | 265 | 9e-57 | Enolase-phosphatase E1 OS=Blastobotrys adeninivorans GN=UTR4 PE=3 SV=1 |
| UniRef50_A0A060T2Y0 | 43.02% | 265 | 2e-53 | Enolase-phosphatase E1 n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A060T2Y0_BLAAD |
| A0A167EJ17_9ASCO | 42.07% | 271 | 2e-52 | Putative acireductone synthase UTR4 OS=Sugiyamaella lignohabitans GN=UTR4 PE=4 SV=1 |
| ENOPH_YARLI | 44.40% | 259 | 3e-51 | Enolase-phosphatase E1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=UTR4 PE=3 SV=1 |
| A0A1E3PRQ9_9ASCO | 40.68% | 263 | 9e-45 | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44759 PE=4 SV=1 |
| A0A1E4TK37_9ASCO | 41.57% | 267 | 4e-44 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_82247 PE=4 SV=1 |
| ENOPH_YEAST | 40.60% | 266 | 3e-42 | Enolase-phosphatase E1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UTR4 PE=1 SV=2 |
| ENOPH_CANAL | 41.56% | 243 | 2e-39 | Enolase-phosphatase E1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UTR4 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0275
Protein family membership
- Enolase-phosphatase E1 (IPR023943)
Domains and repeats
-
Domain
1
50
100
150
200
270
Detailed signature matches
-
-
SSF56784 (HAD-like)
-
-
Protein sequence
>MCA_00683_1 MSKFKALLLDIEGTICPISFVKDTLFPYAKTAISSKISTLGSSFPLTHKPLTSSSSSTKDSENPLLDHLSAFPQEYLSSP QSLLTHILSLIDNDIKDPALKSLQGYLWKDGYVSGIIKAPLYKDAIETIIKASKELQKGVSIYSSGSVAAQKLLLKYTTT IEDTSTTSTTSTTITDSQDLTLLINQYFDTVNAGPKIDPASYDLIASSLGLASSSDDKKSILFLSDNPKEVEAAIKAGLT SYIVIRPGNAPLDDETLKTYKAINTFENLL
GO term prediction
Biological Process
GO:0019509 L-methionine salvage from methylthioadenosine
Molecular Function
GO:0000287 magnesium ion binding
GO:0043874 acireductone synthase activity
Cellular Component
None predicted.