Protein

MCA_00617_1

Length
367 amino acids


Gene name: RTT106

Description: Histone chaperone RTT106

Browser: contigA:1893247-1894351+

RNA-seq: read pairs 599, FPKM 20.1, percentile rank 41.6% (100% = highest expression)

Protein function

Annotation:RTT106Histone chaperone RTT106
EGGNOG:0PI7XRTT106Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell- cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity)
SGD closest match:S000005150RTT106Histone chaperone RTT106
CGD closest match:CAL0000189137RTT106Histone chaperone RTT106

Protein alignments

%idAln lengthE-value
MIA_01384_142.18%3582e-78MIA_01384_1
A0A0J9XKK9_GEOCN41.76%3408e-63Similar to Saccharomyces cerevisiae YNL206C RTT106 Histone chaperone, involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions OS=Geotrichum candidum GN=BN980_GECA25s00219g PE=4 SV=1
UniRef50_A0A0J9XKK941.76%3402e-59Similar to Saccharomyces cerevisiae YNL206C RTT106 Histone chaperone, involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKK9_GEOCN
A0A060SXC6_BLAAD35.07%2114e-26ARAD1A08294p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A08294g PE=4 SV=1
A0A1E4T9Z3_9ASCO33.18%2234e-25Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_124616 PE=4 SV=1
A0A1E3PK93_9ASCO32.49%2375e-20Rtt106-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50899 PE=4 SV=1
RT106_YARLI32.42%2192e-14Histone chaperone RTT106 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=RTT106 PE=3 SV=1
RT106_YEAST41.07%1125e-13Histone chaperone RTT106 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RTT106 PE=1 SV=1
RT106_CANAL37.96%1082e-11Histone chaperone RTT106 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RTT106 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0347

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 367

Detailed signature matches

    1. SSF50729 (PH domain...)
    1. PF08512 (Rtt106)
    2. SM01287 (Rtt106_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_00617_1
MNLETESILSVLPEDLKSKVLQSIEKFPDTLDSFIAVINHFQQANGNVNNKKRKLKEVGESQKQLVVDEKSAIIIPALSI
STPVRKKLDLLLAIDAVVLRKDANTTPDYSIAPSNVETVFLLPIPDKAKPQWALVVVPKLTTTLEIMMATITQDTIKTLI
KPESGELYSGNIQEIILAYFQRRSLPIISKETMPQGQSLLYVPANKGSKDGMLYFLPNFIFYGFKKPLMVIPLNLIVSVS
YSSITTSTFNLIIKYYDKSQPEATEVEFSIIDQKFYDKINHYVNLNGLNDESLAEERKAKVDAKAVFPDQLLKATHEASG
KSNTDPVQPSGNINSQDFNSEDDEEDDDFNEENEEEDSGSDSEEDSE

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.