Protein

MCA_00609_1

Length
370 amino acids

Gene name: RAD51

Description: DNA repair protein RAD51

Browser: contigA:1865645-1867217-

RNA-seq: read pairs 687, FPKM 22.9, percentile rank 45.0% (100% = highest expression)

Protein function

Annotation:RAD51DNA repair protein RAD51
KEGG:K04482RAD51 DNA repair protein RAD51
EGGNOG:0PFFBRAD51DNA repair protein Rad51
SGD closest match:S000000897RAD51DNA repair protein RAD51
CGD closest match:CAL0000180182RAD51Recombinase

Protein alignments

%idAln lengthE-value
MIA_01373_192.33%3260.0MIA_01373_1
A0A0J9XA24_GEOCN89.44%3220.0Similar to Saccharomyces cerevisiae YER095W RAD51 Strand exchange protein, forms a helical filament with DNA that searches for homology OS=Geotrichum candidum GN=BN980_GECA05s04762g PE=3 SV=1
Q59UY8_CANAL81.42%3230.0Recombinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RAD51 PE=3 SV=1
UniRef50_P3660181.56%3203e-177DNA repair protein rhp51 n=206 Tax=Eukaryota TaxID=2759 RepID=RAD51_SCHPO
Q6C1K4_YARLI77.02%3229e-169YALI0F15477p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F15477g PE=3 SV=1
RAD51_YEAST73.44%3204e-157DNA repair protein RAD51 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD51 PE=1 SV=1
A0A167CM09_9ASCO82.92%2812e-158Recombinase RAD51 OS=Sugiyamaella lignohabitans GN=RAD51 PE=3 SV=1
A0A060T5A1_BLAAD63.38%3251e-133ARAD1C10362p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C10362g PE=3 SV=1
A0A1E3PNM9_9ASCO82.50%807e-41Rad51 N-terminal domain-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81649 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0139

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 370

Detailed signature matches

  1. Family IPR016467
    DNA recombination and repair protein, RecA-like
    1. PIRSF005856 (Rad51)
  2. Family IPR011941
    DNA recombination/repair protein Rad51
    1. TIGR02239
  3. Domain IPR010995
    DNA repair Rad51/transcription factor NusA, alpha-helical
    1. SSF47794 (Rad51 N-t...)
  4. Domain IPR013632
    DNA recombination and repair protein Rad51-like, C-terminal
    1. PF08423 (Rad51)
  5. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  6. Domain IPR020588
    DNA recombination and repair protein RecA-like, ATP-binding domain
    1. PS50162 (RECA_2)
  7. Domain IPR033925
    Rad51/DMC1/RadA
    1. cd01123 (Rad51_DMC1...)
  8. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  9. Domain IPR020587
    DNA recombination and repair protein RecA, monomer-monomer interface
    1. PS50163 (RECA_3)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.15...
  2. G3DSA:3.40.50...
  3. PF14520 (HHH_5)
  4. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. multimer (BRC) int...
  4. Walker B motif cd0...

Protein sequence

>MCA_00609_1
MPSEESTSSISQHTTELPPVNGNGSSGATNVIVVPDNVPEDEEELSYGPIPVAKLEGNGINSSDIRKLQAEGYNTVESIA
YTPKRTLLSVKGISEAKADKLLLEASKYVPMGFTTATEFHQRRSELISITTGSKQLDTLLGGGIETGSITEIFGEFRTGK
SQICHTLAVTCQLPIDMGGGEGKCLYIDTEGTFRPSRLLSIGERYGLDGNVALDNVAYARAYNADHQYQLLNQAAAMMAE
SRFSLLIVDSIMALYRTDFSGRGELSARQTHVAKYMRTLQRLADEFGIAVVITNQVVAQVDGGAGMFNPDPKKPIGGNII
AHASTTRLSLRKGRGPQRICKIYDSPSLPESECVFAIYESGIGDPEETDS

GO term prediction

Biological Process

GO:0000724 double-strand break repair via homologous recombination
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:1990426 mitotic recombination-dependent replication fork processing

Molecular Function

GO:0000150 recombinase activity
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0008094 DNA-dependent ATPase activity

Cellular Component

None predicted.