MCA_00589_1

Protein

Length

1,569 amino acids

Gene name: YNG2A

Description: Chromatin modification-related protein YNG2

Browser: contigA:1810659-1815438+

RNA-seq: read pairs 683, FPKM 5.4, percentile rank 18.2% (100% = highest expression)

Protein function

Annotation:		YNG2A	Chromatin modification-related protein YNG2
EGGNOG:	0PJCW	YNG2	Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in cell cycle progression and meiosis
SGD closest match:	S000001132	YNG2	Chromatin modification-related protein YNG2
CGD closest match:	CAL0000174600	YNG2	Chromatin modification-related protein YNG2

Protein alignments

	%id	Aln length	E-value
YNG2_CANAL	53.85%	52	2e-15	Chromatin modification-related protein YNG2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YNG2 PE=3 SV=2
UniRef50_A0A1B7TDY3	52.00%	50	1e-11	Chromatin modification-related protein (Fragment) n=1 Tax=Hanseniaspora valbyensis NRRL Y-1626 TaxID=766949 RepID=A0A1B7TDY3_9ASCO
YNG2_YEAST	44.12%	68	8e-15	Chromatin modification-related protein YNG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YNG2 PE=1 SV=1
A0A1E4TMG0_9ASCO	39.51%	81	7e-15	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1529 PE=4 SV=1
A0A1E3PG82_9ASCO	54.90%	51	5e-14	Chromatin modification-related protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26999 PE=3 SV=1
MIA_03742_1	47.06%	51	4e-13	MIA_03742_1
A0A060TBQ3_BLAAD	34.83%	89	5e-14	Chromatin modification-related protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10274g PE=3 SV=1
A0A0J9XJB4_GEOCN	46.15%	52	6e-13	Chromatin modification-related protein OS=Geotrichum candidum GN=BN980_GECA24s00890g PE=3 SV=1
Q6CGP6_YARLI	44.26%	61	1e-12	YALI0A17490p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A17490g PE=4 SV=1
A0A167F864_9ASCO	38.24%	68	3e-12	Chromatin modification-related protein OS=Sugiyamaella lignohabitans GN=YNG2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1127

Protein family membership

None predicted.

Domains and repeats

Domain
1,486 - 1,566
Zinc finger, RING/FYVE/PHD-type (IPR013083)
Zinc finger, FYVE/PHD-type (IPR011011)
Zinc finger, PHD-type (IPR001965)
Zinc finger, PHD-finger (IPR019787)

1 200 400 600 800 1000 1200 1400 1569

Detailed signature matches

IPR013083

Zinc finger, RING/FYVE/PHD-type
1. G3DSA:3.30.40.10
  
  1,498 - 1,566
  
  GENE3D
  G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
IPR011011

Zinc finger, FYVE/PHD-type
1. SSF57903 (FYVE/PHD ...)
  
  1,486 - 1,551
  
  SUPERFAMILY
  SSF57903 (FYVE/PHD zinc finger)
IPR001965

Zinc finger, PHD-type
1. SM00249 (PHD_3)
  
  1,502 - 1,550
  
  SMART
  SM00249 (PHD_3)
IPR019787

Zinc finger, PHD-finger
1. PS50016 (ZF_PHD_2)
  
  1,500 - 1,552
  
  PROSITE profiles
  PS50016 (ZF_PHD_2)
IPR019786

Zinc finger, PHD-type, conserved site
1. PS01359 (ZF_PHD_1)
  
  1,503 - 1,549
  
  PROSITE patterns
  PS01359 (ZF_PHD_1)

no IPR

Unintegrated signatures

Coil

15 - 35

COILS
Coil (Coil)

708 - 728

COILS
Coil (Coil)
cd15505 (PHD_ING)

1,502 - 1,549

CDD
cd15505 (PHD_ING)
mobidb-lite (disord...)

240 - 279

MobiDB Lite
mobidb-lite (disorder_prediction)

398 - 428

MobiDB Lite
mobidb-lite (disorder_prediction)

532 - 565

MobiDB Lite
mobidb-lite (disorder_prediction)

1,549 - 1,569

MobiDB Lite
mobidb-lite (disorder_prediction)

721 - 935

MobiDB Lite
mobidb-lite (disorder_prediction)

1,081 - 1,500

MobiDB Lite
mobidb-lite (disorder_prediction)

1,020 - 1,057

MobiDB Lite
mobidb-lite (disorder_prediction)

679 - 704

MobiDB Lite
mobidb-lite (disorder_prediction)

489 - 517

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

H3K4me3 binding si...

1,502F

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,514T

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,515M

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,516I

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,517A

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,518C

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,519D

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,526K

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,527W

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,530F

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,538T

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,539P

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,542D

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)

1,544W

H3K4me3 binding site
1,502F, 1,514T, 1,515M, 1,516I, 1,517A, 1,518C, 1,519D, 1,526K, 1,527W, 1,530F, 1,538T, 1,539P, 1,542D, 1,544W
CDD
cd15505 (PHD_ING)
Zn binding site cd...

1,503C

Zn binding site
1,503C, 1,505C, 1,518C, 1,523C, 1,529H, 1,532C, 1,546C, 1,549C
CDD
cd15505 (PHD_ING)

1,505C

Zn binding site
1,503C, 1,505C, 1,518C, 1,523C, 1,529H, 1,532C, 1,546C, 1,549C
CDD
cd15505 (PHD_ING)

1,518C

Zn binding site
1,503C, 1,505C, 1,518C, 1,523C, 1,529H, 1,532C, 1,546C, 1,549C
CDD
cd15505 (PHD_ING)

1,523C

Zn binding site
1,503C, 1,505C, 1,518C, 1,523C, 1,529H, 1,532C, 1,546C, 1,549C
CDD
cd15505 (PHD_ING)

1,529H

Zn binding site
1,503C, 1,505C, 1,518C, 1,523C, 1,529H, 1,532C, 1,546C, 1,549C
CDD
cd15505 (PHD_ING)

1,532C

Zn binding site
1,503C, 1,505C, 1,518C, 1,523C, 1,529H, 1,532C, 1,546C, 1,549C
CDD
cd15505 (PHD_ING)

1,546C

Zn binding site
1,503C, 1,505C, 1,518C, 1,523C, 1,529H, 1,532C, 1,546C, 1,549C
CDD
cd15505 (PHD_ING)

1,549C

Zn binding site
1,503C, 1,505C, 1,518C, 1,523C, 1,529H, 1,532C, 1,546C, 1,549C
CDD
cd15505 (PHD_ING)

Protein sequence

>MCA_00589_1
MDLLAQDLCKSNLLIANLNNRARDVSSRLDGAISQLSQQLSKISHSIGTPKDESINKEENANQLVQKKSEDSTSTDQDLS
LVDTFQKIIQLTEKKVSLYSNSYAEAVRIKTHVEQMKNLVENELGRISDYLSSTAAYELIQRIEAIENNIPSSELKELIE
SQQSQLNLSRFQENDTKLEPHFSIDAENNIIEPKSVVHQQLHAIYASDGDADEEESISDDSLSEFDEISLLNFDEEEISF
TGDASEAKPESQQFQPTGEYDSKYSQASKPNEKADTIPDTQQYELLDLISDVGNKRAHRHARGALSVVRHNKLDNDSDED
YQLVNTSQNEIFHQNQLKLIKLLTDLGMNRNQDMVLPKYIEFYGGDPQDALEQLLNIDSLDFLEYFLDKRLISISTRNSS
PVKRGKRGRRPKTPQTPIDMSRNTDTDSETEKVLFLGETPLSSDIKPNSVNNSSGTNIIRSLNKTPSIDEAKRAGISPTQ
FYQPVDFPKNRVRIGRPPGSYKIKRDPVTGQPVGKPNYKYSHEMYLKRKMKALNSSDSSNSNSSPISRQRRGRVKHVQAR
AQSMDSITNGKVDQATDAFEIAEAKSFSRSSTQEKAGTLESLANEYNSEDDVSLSRQVQMPVDEKDLSADKKINDFGFSN
GQMQIDQAKLLDKEDLKSDVHSSEPETTDRANTILVANTNQQETQEDSRIENEHEKVDDITNRHALSDSELYNLADDIEK
ELEEAQNSQNLPSPKEEDSEKENTIKEETEYSKDDISIGDFSFQADDNSKMDSLEDLIEHNTEAANSDDHDYRNDRDDSV
DIIAEVKTESQENIQSDPLKSREPSVEYGDILNEDLNKPMHADNPEHNSSEVLQPDTHNSPLSEIDSQKADIPTEEGSIM
HKAESDSIDSSTYNSENTASNKSENSQDASLDNHEKNSSNDTQANNTFLATSMNNYETKADLAEIPRPSKDSMDPSINTE
STISKAIEIKPNEDNRSEVVEDTKIAGPFISPSYPVVISYPGSKSQSPVLDEEDNCKPLEKMAPEPECFSNDSSLGSQQI
NSQNSFEPKDGVEGCIDATIENPNEDMLEFQIDPELLYHTTLSKSESSESSKVDPKEVEISEDRTVEEGARMLSPAKQDP
LESDISQNTNIQYDNNLNLGHSNDEKEEDSQADKPDNKTKASIPINNKFSNQTEESPFASLALEKSEPNQEIEPAVNEES
SAENNFSAKESEFVLAEDAELKTETRIESQNENFNQDDKKRPSNQTSQYTTDLASDHGILTKSDHEKEKLPVDQNSNHFP
EPVSTEVSTQKAELAQPHENNILNQKSASEAEVEPEPTDSKSFIESTKNQEFEASKTLEPADGVQTDDKVSNDGPTVTAE
PELFTKSKKRKAEVQVEIRKSKRQAARLASSTTPNPPTTDDTSASKEQKIKKEIVIKEEPGETKKSTDKSSVTKRITRSK
TPPAKIKKEKGATTVATATESKAIKPEKSSTKRGKSKEPQGSTTIGSRRGRPPKSKPSNESFCFCRRAEIAGDTMIACDN
EKCKYKWFHFSCLNLTETPTSDSWYCPDCSKEASSSSNSSTKKIKKARK

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MCA_00589_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component