Protein
MCA_00405_1
Length
360 amino acids
Gene name: ERG3A
Description: Delta(7)-sterol 5(6)-desaturase
Browser: contigA:1272539-1273622-
RNA-seq: read pairs 5674, FPKM 194.2, percentile rank 87.7% (100% = highest expression)
Protein function
| Annotation: | ERG3A | Delta(7)-sterol 5(6)-desaturase | |
|---|---|---|---|
| KEGG: | K00227 | SC5DL | Delta7-sterol 5-desaturase [EC:1.14.19.20] |
| EGGNOG: | 0PG6G | ERG3 | C-5 sterol desaturase |
| SGD closest match: | S000004046 | ERG3 | Delta(7)-sterol 5(6)-desaturase |
| CGD closest match: | CAL0000190948 | ERG3 | C-5 sterol desaturase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01462_1 | 54.27% | 363 | 9e-140 | MIA_01462_1 |
| A0A0J9XE52_GEOCN | 53.55% | 366 | 4e-132 | Similar to Saccharomyces cerevisiae YLR056W ERG3 C-5 sterol desaturase, glycoprotein that catalyzes the introduction of a C-5(6) double bond into episterol, a in ergosterol biosynthesis OS=Geotrichum candidum GN=BN980_GECA11s03013g PE=3 SV=1 |
| A0A060TCV3_BLAAD | 50.42% | 355 | 8e-125 | ARAD1D42438p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42438g PE=3 SV=1 |
| ERG3_YEAST | 50.83% | 360 | 8e-119 | Delta(7)-sterol 5(6)-desaturase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG3 PE=1 SV=1 |
| UniRef50_P32353 | 50.83% | 360 | 2e-115 | Delta(7)-sterol 5(6)-desaturase n=267 Tax=Fungi TaxID=4751 RepID=ERG3_YEAST |
| A0A167FFQ0_9ASCO | 47.15% | 386 | 3e-115 | C-5 sterol desaturase OS=Sugiyamaella lignohabitans GN=ERG3 PE=3 SV=1 |
| A0A1E3PJ47_9ASCO | 48.60% | 358 | 6e-115 | Sterol delta 5,6-desaturase ERG3 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51972 PE=3 SV=1 |
| Q59VG6_CANAL | 48.28% | 377 | 8e-113 | C-5 sterol desaturase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG3 PE=3 SV=1 |
| Q6C8C2_YARLI | 47.63% | 359 | 2e-112 | YALI0D20878p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D20878g PE=3 SV=1 |
| A0A1E4TL63_9ASCO | 43.96% | 364 | 4e-99 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30630 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3252
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
360
Detailed signature matches
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PF04116 (FA_hydroxy...)
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no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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-
TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_00405_1 MDIVLETFDNLILDKAYARIVPKNAQIPPILEKLLMVQKLPQLVSNIPLDTNSTIDQVTDIWHRVPASEIYGQIPFFFET SSYASKSLLPRDNIMRQFISLTILTSILGIALYLTTAWFSYVFFFDKEIFKHPKYKKNQMAMEIKQAVFAIPFMSIFAAF CFTFEIRGYSKLYWKLDEYPAWYFLGQVAAFFLFTDLGVYIAHRGLHHPKVYKYLHKTHHKWIVSTPFASHAFHPMDGFI QSIPYHMFPFIFPVQKAIYLFLFMIINVGTVLIHDGNFFMNNGIIHGTACHAVHHLYFNYNYGQYTTLWDRLGGSYRKPE DELFQTTFKQDDKTWQKQSEKIDKILLEVDGDEEVTSSEK
GO term prediction
Biological Process
GO:0008610 lipid biosynthetic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
Cellular Component
None predicted.