Protein

MIA_01462_1

Length
376 amino acids

Browser: contig02:793435-794566-

Protein function

EGGNOG:0PG6GERG3C-5 sterol desaturase
SGD closest match:S000004046ERG3Delta(7)-sterol 5(6)-desaturase
CGD closest match:CAL0000190948ERG3C-5 sterol desaturase

Protein alignments

%idAln lengthE-value
MCA_00406_172.368%3800.0MCA_00406_1
A0A0J9XE52_GEOCN61.333%3754.09e-172Similar to Saccharomyces cerevisiae YLR056W ERG3 C-5 sterol desaturase, glycoprotein that catalyzes the introduction of a C-5(6) double bond into episterol, a in ergosterol biosynthesis OS=Geotrichum candidum GN=BN980_GECA11s03013g PE=3 SV=1
A0A060TCV3_BLAAD51.862%3768.88e-143ARAD1D42438p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42438g PE=3 SV=1
A0A1E3PJ47_9ASCO51.724%3777.10e-142Sterol delta 5,6-desaturase ERG3 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51972 PE=3 SV=1
ERG3_YEAST51.444%3812.05e-138Delta(7)-sterol 5(6)-desaturase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG3 PE=1 SV=1
UniRef50_P3235351.444%3814.91e-135Delta(7)-sterol 5(6)-desaturase n=267 Tax=Fungi TaxID=4751 RepID=ERG3_YEAST
Q6C8C2_YARLI50.133%3778.98e-138YALI0D20878p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D20878g PE=3 SV=1
Q59VG6_CANAL51.295%3861.63e-135C-5 sterol desaturase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG3 PE=3 SV=1
A0A167FFQ0_9ASCO50.498%4027.69e-134C-5 sterol desaturase OS=Sugiyamaella lignohabitans GN=ERG3 PE=3 SV=1
A0A1E4TL63_9ASCO46.089%3581.56e-114Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30630 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3209

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 376

Detailed signature matches

  1. Domain IPR006694
    Fatty acid hydroxylase
    1. PF04116 (FA_hydroxy...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_01462_1
MDLILEVVDSFVFDKAYATIFPNTIQLPTFLQKLLQVKSVALAATDPSFLDSVWANASTPALLQTHTLATLFQETSPEIY
GKAPFLMEASQYVSQSLFLRDNVFRQILSMTVIISVFGFILYFFTALLAYVTVFDKETFNHPKYLKNQIYMEIYQAVSAI
PVMSFLTALFFALELHGYSKLYFRTSDYPFWYLIFQFPLFVFFTDMGVYIAHRGLHHPRFYKRFHKPHHKWIVSTPFASH
AFHPIDGFVQSVPYHIFPFIFPLHKISYLLLFVFVNMWTVMIHDGYFIMNNIFVNGTACHTIHHLYFNYNYGQYTTLWDR
IGNSYRRPEDELFNEGLKNDRNTWKKQSQKMEEIVKEVEGGDNRVYLHADDDKKSK

GO term prediction

Biological Process

GO:0008610 lipid biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.