Protein

MCA_00399_1

Length
599 amino acids

Description: DEAD/DEAH box helicase

Browser: contigA:1256118-1257984-

RNA-seq: read pairs 443, FPKM 9.1, percentile rank 24.5% (100% = highest expression)

Protein function

Annotation:DEAD/DEAH box helicase
EGGNOG:0PQWJDEAD/DEAH box helicase
SGD closest match:S000005056DBP2ATP-dependent RNA helicase DBP2
CGD closest match:CAL0000188191PRP5Pre-mRNA-processing ATP-dependent RNA helicase PRP5

Protein alignments

%idAln lengthE-value
MIA_01457_141.10%6011e-152MIA_01457_1
A0A0J9XC14_GEOCN38.08%6258e-100Similar to Saccharomyces cerevisiae YLR276C DBP9 ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit OS=Geotrichum candidum GN=BN980_GECA08s03865g PE=4 SV=1
UniRef50_A0A0J9XC1438.08%6252e-96Similar to Saccharomyces cerevisiae YLR276C DBP9 ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XC14_GEOCN
A0A1E3PM83_9ASCO30.27%5659e-60Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50223 PE=4 SV=1
A0A167DL74_9ASCO29.90%5255e-51Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1312 PE=4 SV=1
Q6CF17_YARLI25.79%5703e-26YALI0B11066p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11066g PE=4 SV=1
PRP5_CANAL33.60%1251e-11Pre-mRNA-processing ATP-dependent RNA helicase PRP5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRP5 PE=3 SV=1
A0A1E4TI63_9ASCO37.01%1272e-12Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32059 PE=4 SV=1
A0A060T1R6_BLAAD31.22%1897e-11ARAD1C26818p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C26818g PE=3 SV=1
DBP2_YEAST31.32%1824e-10ATP-dependent RNA helicase DBP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DBP2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9777
Predicted cleavage: 32

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 599

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014014
    RNA helicase, DEAD-box type, Q motif
    1. PS51195 (Q_MOTIF)
  3. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  4. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...

Protein sequence

>MCA_00399_1
MFSSGKQRIRPYVLFSSHRPLLFQRNSSNRQRVLNRIRDKIVQDHDYMVNNEEGVRLKIDPKQIKTFEDFKFQNGILNAL
KAEFPDIKHPTQIQKNLLSLLKSDLSVLAASPPGTGKSLATALFLLSHTPDKLLQSDTPSISNLLIVPTPDLASQYYNII
KKLTSKSGINENQVVQCIYRADAESERKQIELLKKYPAPHVLIGTPTRILDILSSPNLKLLPLFNLSFIAVDEADRLLPK
ICLYSSFEKNNKFVAKDFKHSVPTQVLLNFLVPWRDNYVSANNDYFFPLRFLLESSTASNNLKLICSKNNWIKGRTMLRL
GTDKVGGEMRERIANDVSSYFVSFNPQTGILTDTNFDISNIIPEFDDKAFDIIGEMNDRRKKDYMRKFSKLSKDGKTNLL
KLYAIALARTIELDFEKSKETFKRRSLVIIPEGYSIDYFLEILKKHTGITGARSRIIDNKCAIFYNKSENELAEIDPETF
FSTKINPDKPDDELPQVLVYRASECVGLDFPDLSRIYVLSWDSILSSKLYLSLAGRCRVAPINERGEKSQTGSWKEPTDP
EQGRCVVISTTDELNDDKYRALLIGSMKKIAVSNSKYFS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0005524 ATP binding

Cellular Component

None predicted.