Protein

MCA_00345_1

Length
140 amino acids

Gene name: TRX1A

Description: Thioredoxin

Browser: contigA:1108068-1108491-

RNA-seq: read pairs 29940, FPKM 2623.7, percentile rank 98.2% (100% = highest expression)

Protein function

Annotation:TRX1AThioredoxin
KEGG:K03671trxA thioredoxin 1
EGGNOG:0PQT5TRX2Thioredoxin
SGD closest match:S000004033TRX1Thioredoxin-1
CGD closest match:CAL0000180451TRX1Thioredoxin

Protein alignments

%idAln lengthE-value
A0A1E3PG15_9ASCO66.34%1016e-37Thioredoxin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47429 PE=3 SV=1
A0A167EUJ2_9ASCO60.00%1002e-32Thioredoxin OS=Sugiyamaella lignohabitans GN=TRX1 PE=3 SV=1
A0A0J9XEQ5_GEOCN52.63%1336e-32Thioredoxin OS=Geotrichum candidum GN=BN980_GECA12s02155g PE=3 SV=1
Q6C399_YARLI58.25%1038e-32Thioredoxin OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F01496g PE=3 SV=1
UniRef50_Q6C39958.25%1032e-28Thioredoxin n=3 Tax=Dipodascaceae TaxID=34353 RepID=Q6C399_YARLI
MIA_06006_156.86%1023e-30MIA_06006_1
TRX1_YEAST60.20%983e-29Thioredoxin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRX1 PE=1 SV=3
A0A1E4TI34_9ASCO56.00%1003e-29Thioredoxin OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3115 PE=3 SV=1
A0A060T572_BLAAD46.88%1284e-29Thioredoxin OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C03476g PE=3 SV=1
A0A1D8PU69_CANAL48.48%995e-25Thioredoxin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TRX1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9241
Predicted cleavage: 37

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 140

Detailed signature matches

  1. Family IPR005746
    Thioredoxin
    1. TIGR01068
    2. PIRSF000077 (Thiore...)
  2. Domain IPR012336
    Thioredoxin-like fold
    1. SSF52833 (Thioredox...)
  3. Domain IPR013766
    Thioredoxin domain
    1. PF00085 (Thioredoxin)
    2. PS51352 (THIOREDOXIN_2)
  4. SITE IPR017937
    Thioredoxin, conserved site
    1. PS00194 (THIOREDOXIN_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.30.10
  2. PR00421 (THIOREDOXIN)
  3. SFLDG00337 (Thiored...)
  4. SFLDG00345 (PDI-like)
  5. cd02947 (TRX_family)

Residue annotation

  1. SFLDG00337
  2. catalytic residues...

Protein sequence

>MCA_00345_1
MFRPSILKQTTNLLFSTKPLSTTTSLRYFSSTNTIKMPVKPIKNLSEFQSAIAFEGLTVVDFYAVWCGPCKMISPVLEKL
SNNYTQAQFLKVDVDEAADVAQEYAVAAMPTFIFFKNGQKVETIVGANPQKLQAFIAQNA

GO term prediction

Biological Process

GO:0006662 glycerol ether metabolic process
GO:0045454 cell redox homeostasis

Molecular Function

GO:0015035 protein disulfide oxidoreductase activity

Cellular Component

None predicted.