Protein
MCA_00335_1
Length
564 amino acids
Gene name: PDC1
Description: Pyruvate decarboxylase isozyme 1
Browser: contigA:1037658-1039436+
RNA-seq: read pairs 147345, FPKM 3222.3, percentile rank 98.7% (100% = highest expression)
Protein function
Annotation: | PDC1 | Pyruvate decarboxylase isozyme 1 | |
---|---|---|---|
KEGG: | K01568 | PDC | pyruvate decarboxylase [EC:4.1.1.1] |
EGGNOG: | 0PHI5 | PDC1 | Pyruvate decarboxylase |
SGD closest match: | S000004034 | PDC1 | Pyruvate decarboxylase isozyme 1 |
CGD closest match: | CAL0000201027 | PDC11 | Pyruvate decarboxylase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_00052_1 | 71.81% | 564 | 0.0 | MIA_00052_1 |
A0A0J9XD52_GEOCN | 62.21% | 561 | 0.0 | Similar to Saccharomyces cerevisiae YLR044C PDC1 Major of three pyruvate decarboxylase isozymes OS=Geotrichum candidum GN=BN980_GECA08s04300g PE=3 SV=1 |
PDC1_CANAL | 59.30% | 570 | 0.0 | Pyruvate decarboxylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PDC11 PE=1 SV=2 |
PDC1_YEAST | 58.79% | 563 | 0.0 | Pyruvate decarboxylase isozyme 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDC1 PE=1 SV=7 |
UniRef50_P06169 | 58.79% | 563 | 0.0 | Pyruvate decarboxylase isozyme 1 n=132 Tax=Ascomycota TaxID=4890 RepID=PDC1_YEAST |
A0A060TB88_BLAAD | 59.93% | 564 | 0.0 | ARAD1D26004p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26004g PE=3 SV=1 |
A0A161HH14_9ASCO | 57.22% | 561 | 0.0 | Indolepyruvate decarboxylase 1 OS=Sugiyamaella lignohabitans GN=PDC1 PE=3 SV=1 |
A0A1E3PK22_9ASCO | 55.30% | 566 | 0.0 | Pyruvate decarboxylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46404 PE=3 SV=1 |
Q6C9L5_YARLI | 56.81% | 565 | 0.0 | YALI0D10131p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D10131g PE=3 SV=1 |
A0A1E4TLE4_9ASCO | 55.24% | 525 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30685 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0813
Protein family membership
- Thiamine pyrophosphate (TPP)-dependent enzyme (IPR012110)
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
564
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
TPP binding site c...
-
PYR/PP interface c...
-
dimer interface cd...
-
TPP-binding site c...
-
dimer interface cd...
Protein sequence
>MCA_00335_1 MSEITVGHYIFERLKQIGIKSIFGVPGDFNLALLDKIYDVEGLRWVGNTNELNAGYAADGYARVNGIAALVTTFGVGELS AVNAVAGAYAEHVPVIHIVGIPAVSAQNKHLLLHHTLGNGDFHVFHKMSQGISEKVTVLNDTHHLTAKIDDIIKVAKTTQ RPVYLGLPTNIGEVKVNSKDLETPIDFSLPPNDKEAEDECLSLIVETIEKAENPIILVDACASRHNVIEQTRKLCRLTKF PVFTTPMGKSVINEDYERYGGVYVGSLSSPEIFKAVEDSDLIISVGALLSDFNTGSFTYHYKTNNIIEFHSNYIGIRKAT YQGVRMGPVLDRLVETLKPTDINAKLTPVPPLVKAPKEPSDESGLTHEYLWPRISGFLKSGDIIVSETGTSSFGITATVF PANVIGISQVLWGSIGYSVGCTLGAALAAQEIDPKRRVILFVGDGSLQLTVAAISTMIRWKLNPYLFVLNNNGYTIERLI HGPEAEYNNIQPWDHQLLLKVFGAKEDESESIRLSSKKELDTLFKDETFNNPAKIRLIELMLDRLDSPASLIKQGELTSK TNSS
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0016831 carboxy-lyase activity
GO:0030976 thiamine pyrophosphate binding
Cellular Component
None predicted.