Protein
MCA_00265_1
Length
323 amino acids
Gene name: LIP2
Description: Octanoyltransferase, mitochondrial
Browser: contigA:809312-810284-
RNA-seq: read pairs 283, FPKM 10.8, percentile rank 27.2% (100% = highest expression)
Protein function
| Annotation: | LIP2 | Octanoyltransferase, mitochondrial | |
|---|---|---|---|
| KEGG: | K03801 | lipB | lipoyl(octanoyl) transferase [EC:2.3.1.181] |
| EGGNOG: | 0PPYW | FG08693.1 | Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) |
| SGD closest match: | S000004229 | LIP2 | Octanoyltransferase, mitochondrial |
| CGD closest match: | CAL0000185298 | orf19.3010 | Octanoyltransferase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9YHE7_GEOCN | 43.07% | 274 | 5e-63 | Octanoyltransferase OS=Geotrichum candidum GN=BN980_GECA01s03189g PE=3 SV=1 |
| UniRef50_A0A0J9YHE7 | 43.07% | 274 | 1e-59 | Octanoyltransferase n=3 Tax=saccharomyceta TaxID=716545 RepID=A0A0J9YHE7_GEOCN |
| MIA_05141_1 | 42.80% | 250 | 7e-58 | MIA_05141_1 |
| A0A060TBU4_BLAAD | 43.52% | 216 | 3e-52 | Octanoyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B11352g PE=3 SV=1 |
| A0A1E4TH78_9ASCO | 44.51% | 182 | 2e-42 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11983 PE=4 SV=1 |
| A0A1E3PQ83_9ASCO | 42.86% | 203 | 7e-40 | Lipoyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81627 PE=4 SV=1 |
| Q6C069_YARLI | 38.22% | 225 | 5e-38 | Octanoyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27357g PE=3 SV=1 |
| LIPB_YEAST | 31.34% | 201 | 6e-27 | Octanoyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LIP2 PE=1 SV=1 |
| Q5AI42_CANAL | 34.54% | 194 | 4e-26 | Octanoyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3010 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9053
Predicted cleavage: 23
Protein family membership
- Octanoyltransferase (IPR000544)
Domains and repeats
-
Domain
1
50
100
150
200
250
323
Detailed signature matches
-
-
PIRSF016262 (LPLase)
-
-
-
PS51733 (BPL_LPL_CA...)
-
-
-
PS01313 (LIPB)
-
no IPR
Unintegrated signatures
-
-
-
SSF55681 (Class II ...)
Protein sequence
>MCA_00265_1 MSFIKKDPASCLRIIPKIVYNSNASSSTLPSIGTKLLWKNYTISPREYTFGSQEMNQIVENFLSFKKNHPRCPDIYDPEL QKEGSSSILKPPPPTLLTFEFKNVYTIGRRDKGKMSKQELDIISGNGTYPVEETQRGGQTTFHGLGQLVAYPIIDLNSFY TYNSDLPPLTPKEVSLQIERDSLKSGIPVRCYVELLERSVIASLAKGWGLDGTFVTENTGVWTTPETKICAMGVQVRRHI TSHGIGLNISTDLGMFQRITACGLPDKQATSVLEEIRRRRMNEFLKDSKNNEKLTVGYAAKTFAEELAEGLGLELEQQDI PLI
GO term prediction
Biological Process
GO:0006464 cellular protein modification process
GO:0009107 lipoate biosynthetic process
Molecular Function
GO:0016415 octanoyltransferase activity
GO:0033819 lipoyl(octanoyl) transferase activity
Cellular Component
GO:0005737 cytoplasm