Protein
MCA_00144_1
Length
298 amino acids
Gene name: PNP1
Description: Purine nucleoside phosphorylase
Browser: contigA:386262-387459+
RNA-seq: read pairs 457, FPKM 18.9, percentile rank 40.0% (100% = highest expression)
Protein function
| Annotation: | PNP1 | Purine nucleoside phosphorylase | |
|---|---|---|---|
| KEGG: | K03783 | punA | purine-nucleoside phosphorylase [EC:2.4.2.1] |
| EGGNOG: | 0PFFJ | PGUG_02689 | The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) |
| SGD closest match: | S000004199 | PNP1 | Purine nucleoside phosphorylase |
| CGD closest match: | CAL0000198365 | PNP1 | Purine nucleoside phosphorylase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00495_1 | 76.25% | 299 | 7e-170 | MIA_00495_1 |
| A0A0J9X6E3_GEOCN | 70.43% | 301 | 3e-158 | Purine nucleoside phosphorylase OS=Geotrichum candidum GN=BN980_GECA04s02969g PE=3 SV=1 |
| A0A060T5F1_BLAAD | 61.90% | 294 | 2e-135 | Purine nucleoside phosphorylase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B06600g PE=3 SV=1 |
| Q6BZX6_YARLI | 57.43% | 296 | 7e-127 | Purine nucleoside phosphorylase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F30129g PE=3 SV=1 |
| A0A1E3PE47_9ASCO | 55.25% | 295 | 2e-119 | Purine nucleoside phosphorylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53795 PE=3 SV=1 |
| A0A1D8PJL8_CANAL | 59.27% | 275 | 1e-117 | Purine nucleoside phosphorylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PNP1 PE=3 SV=1 |
| UniRef50_Q9UTG1 | 56.00% | 300 | 1e-112 | Putative purine nucleoside phosphorylase n=102 Tax=cellular organisms TaxID=131567 RepID=PNPH_SCHPO |
| A0A167DBA2_9ASCO | 61.09% | 239 | 6e-107 | Purine-nucleoside phosphorylase OS=Sugiyamaella lignohabitans GN=PNP1 PE=4 SV=1 |
| A0A1E4TJD6_9ASCO | 51.34% | 298 | 2e-103 | Purine nucleoside phosphorylase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30169 PE=3 SV=1 |
| PNPH_YEAST | 53.02% | 281 | 7e-101 | Purine nucleoside phosphorylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PNP1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0704
Protein family membership
- Purine nucleoside phosphorylase (IPR011268)
Domains and repeats
-
Domain
1
50
100
150
200
250
298
Detailed signature matches
-
-
-
PIRSF000477 (PurNPase)
-
-
-
PS01240 (PNP_MTAP_2)
-
no IPR
Unintegrated signatures
Protein sequence
>MCA_00144_1 MTDTYEKASNAAEFIKKLYPSGYESPKVAIICGTGLGGIANILDSSSVVEIPYKDIPGFMVSTVHGHAGKLLLGYIGSNK VPVICMVGRFHSYEGYEIYDTVFPVRVFNLLGVPVLIATNAAGGLNKAYQVGDIMVLDDHINFPGFAGLHPLKGLNDERF GTRFLPLTDTYDHELRSLIFKAAESLDISRSIHEGTYAFVSGPTFETRAESRYLITIGADVVGMSTVPEIITARHGGIRT LALSLVTNVAVVDKPISGKEKLTTDMSEGMASHEEVLEAGQAASKDVEKIIEFVVNNI
GO term prediction
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009116 nucleoside metabolic process
Molecular Function
GO:0003824 catalytic activity
GO:0004731 purine-nucleoside phosphorylase activity
GO:0016763 transferase activity, transferring pentosyl groups
Cellular Component
None predicted.