MCA_00122_1
Gene name: NIP1
Description: Eukaryotic translation initiation factor 3 subunit C
Browser: contigA:329336-332224+
RNA-seq: read pairs 13758, FPKM 189.3, percentile rank 87.4% (100% = highest expression)
Protein function
| Annotation: | NIP1 | Eukaryotic translation initiation factor 3 subunit C | |
|---|---|---|---|
| KEGG: | K03252 | EIF3C | translation initiation factor 3 subunit C |
| EGGNOG: | 0PGWD | NIP1 | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity) |
| SGD closest match: | S000004926 | NIP1 | Eukaryotic translation initiation factor 3 subunit C |
| CGD closest match: | CAL0000176830 | NIP1 | Eukaryotic translation initiation factor 3 subunit C |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04113_1 | 68.77% | 759 | 0.0 | MIA_04113_1 |
| A0A0J9X4G8_GEOCN | 59.76% | 763 | 0.0 | Eukaryotic translation initiation factor 3 subunit C OS=Geotrichum candidum GN=NIP1 PE=3 SV=1 |
| A0A167EKD9_9ASCO | 54.30% | 779 | 0.0 | Eukaryotic translation initiation factor 3 subunit C OS=Sugiyamaella lignohabitans GN=NIP1 PE=3 SV=1 |
| EIF3C_YARLI | 52.19% | 755 | 0.0 | Eukaryotic translation initiation factor 3 subunit C OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NIP1 PE=3 SV=1 |
| UniRef50_Q6C855 | 52.19% | 755 | 0.0 | Eukaryotic translation initiation factor 3 subunit C n=6 Tax=Saccharomycetales TaxID=4892 RepID=EIF3C_YARLI |
| A0A060TDK6_BLAAD | 53.26% | 766 | 0.0 | Eukaryotic translation initiation factor 3 subunit C OS=Blastobotrys adeninivorans GN=NIP1 PE=3 SV=1 |
| A0A1E3PS68_9ASCO | 49.87% | 766 | 0.0 | Eukaryotic translation initiation factor 3 subunit C OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NIP1 PE=3 SV=1 |
| A0A1E4TIG4_9ASCO | 43.01% | 730 | 7e-177 | Eukaryotic translation initiation factor 3 subunit C OS=Tortispora caseinolytica NRRL Y-17796 GN=NIP1 PE=3 SV=1 |
| EIF3C_CANAL | 36.88% | 762 | 4e-130 | Eukaryotic translation initiation factor 3 subunit C OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NIP1 PE=3 SV=2 |
| EIF3C_YEAST | 35.36% | 707 | 3e-126 | Eukaryotic translation initiation factor 3 subunit C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NIP1 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1705
Predicted cleavage: 29
Protein family membership
Domains and repeats
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Domain
-
Domain
Detailed signature matches
no IPR
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SM00753 (PINT)
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mobidb-lite (disord...)
Protein sequence
>MCA_00122_1 MQIQKFFTSPQTKSIIPHPPKGRLANRIGPADCKRRFKPPFETSDSSEEESSSSEEELYESSEEEQSSEEESSEEEDSEE DSDDDSDSDSESDSGKGKKASAFLKSKFLKGSHSDSDDESDDESKRVVKSAKDKLLDEIDSCIKTIDNGKKINDWVAISS EFEKLNKNVERIMKQFNTTPKQYIKAIVELEAFAQEATKAQKSSKKKMNALNLKALNATTQKVKKNNKGYEKLIAQYNAD SDAFMNESVEESSEDKPKVKGIKASFTASHSAGADDDSGFTTVGKAATTDTDAFSVLKSVVESRGRKGVDNEEQARLLES IYKETKEVYVKIVLLLRLIPLKLDIAAATPKESVEIWNSTKKYVDNLLDILDENFSKYQLSDSAPEPEELEKGLPPREDG VQEIPGSIVSIVERLDDEFTHSLVDIDPHTTEYVDRLRDESGLYAVILRTQIYLERTTKLKFEEYESISRILSRRVDRIY FKPNVVVIAGEKAAWSTIDSSLDSKISPRIPESVPEDYVTSLINGICSVLYQQSNLLFRTRAILCHIYNYALNDKYYKAR DLMLMSHIQSSIATAEIPLQILYNRTLVQIGICAFRNGLIAECQQTLAESSASSRLKELLGQGVAKNINNSSTEGRQRLL PFHMHINLEFLECINLTSAMLIEVPSMVASEKQIDGKKKVISRTFRRMLDYNTRQVFTGPPENTRDHIMQAARALLECEW KKARDLLNSIKIWDLLPNPEDIKKMLGEKLQVEGLRTYLFRYGATYRSLSFATLSTLFDLSERRITVIISKMIANEEIDA ALDQKTNSVIFRQGVELSRLQNLASALAEKAVQLVERNERLAGGQALPEQAPRTNTNSNNASNTGSSHNNQNQSSSNSGR NNRSDGRRNQTRATARA
GO term prediction
Biological Process
GO:0006413 translational initiation
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0031369 translation initiation factor binding
Cellular Component
GO:0005852 eukaryotic translation initiation factor 3 complex