Protein
MIA_mt_19350964
Length
664 amino acids
Browser: mtDNA:25596-27591+
Protein function
| EGGNOG: | 0PTMR | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) | |
|---|---|---|---|
| CGD closest match: | CAL0000188422 | NAD5 | NADH-ubiquinone oxidoreductase chain 5 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0A1I5R0_GEOCN | 82.838% | 606 | 0.0 | NADH-ubiquinone oxidoreductase chain 5 OS=Geotrichum candidum GN=ND5 PE=3 SV=1 |
| MCA_mt_19351067 | 78.120% | 617 | 0.0 | MCA_mt_19351067 |
| A0A060RCS4_BLAAD | 65.719% | 598 | 0.0 | NADH-ubiquinone oxidoreductase chain 5 OS=Blastobotrys adeninivorans GN=nd5 PE=3 SV=1 |
| A0A161HIF4_9ASCO | 66.384% | 589 | 0.0 | NADH-ubiquinone oxidoreductase chain 5 OS=Sugiyamaella lignohabitans GN=AWJ20_5368 PE=3 SV=1 |
| UniRef50_G4U516 | 54.392% | 592 | 0.0 | NADH-ubiquinone oxidoreductase chain 5 n=3 Tax=Candida TaxID=1535326 RepID=G4U516_9ASCO |
| NU5M_YARLI | 53.716% | 592 | 0.0 | NADH-ubiquinone oxidoreductase chain 5 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ND5 PE=1 SV=1 |
| NU5M_CANAL | 49.362% | 549 | 1.38e-140 | NADH-ubiquinone oxidoreductase chain 5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NAD5 PE=3 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8216
Predicted cleavage: 31
Protein family membership
- NADH-plastoquinone oxidoreductase, chain 5 (IPR003945)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
664
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
PR01434 (NADHDHGNASE5)
-
-
TRANSMEMBRANE (Tran...)
Protein sequence
>MIA_mt_19350964 MMFMTMFMPMLGSMLAGLLGRWLGYKLSGYVATLSMMMACMFSYMLYYNVMMNNEMYTLNMGKWMYVEYLEMDWSFMMDE LTVTMLMPMLTVSSLVHMYALGYMSHDPHQSRFFSMLAMFTGFMVMLVTGDNYLVMFLGWEFIGLASYLLISFWFTRLAA MKSALSALLMNKFGDTFLSMGLMMMIWTFGSLNYNSMFALSQFINTDMLNTIMICFLIGATSKSAQLGLHNWLLSSMEGP TPVSALLHAACLVCAGMYLLIRSSYMLEYSPTVLLMCLWLGGLTTMMAGMMAMTSNDMKKIMALSTMSQLGLMVVAIGLS AYNMSLFHLFCHAMFKALLFMSAGSIMHSMISESQDIRTYGGLLNYLPVTYVCILMASLSLMAFPGLTGFYSKDIIIEST LGVYTISGYIIYWLSLSSATLTTLYSIRLLYLVFYNIPNNNRYTYFNLHESTWFMLIPMIILSFASIFIGYITRDIYLGF GSKFNSMFMHPNNLSIIDTELALPSSNLLLKLLPLMFTMLGTMIVIVLYEFKYSLIYVYNNKLLLNLYMFFNNKLMLDQM LNNIILRSNLSLGFKLNKFVDKGALQILGPRGIYDTLNIIVYNLIKLSTGSLLHFSIYLLSGIIMLLLMLTNLFNISLPS HGEGAILFIFLIISFITPSKNVKV
GO term prediction
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:0055114 oxidation-reduction process
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Cellular Component
None predicted.