Protein

MIA_06375_1

Length
389 amino acids

Browser: contig11:231076-232619+

Protein function

EGGNOG:0PHJ3CPR6Peptidyl-prolyl cis-trans isomerase
SGD closest match:S000004206CPR6Peptidyl-prolyl cis-trans isomerase CPR6
CGD closest match:CAL0000193303CPR6Peptidyl-prolyl cis-trans isomerase D

Protein alignments

%idAln lengthE-value
A0A0J9XD24_GEOCN68.041%3881.96e-170Similar to Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (Cyclophilin) OS=Geotrichum candidum GN=BN980_GECA11s00670g PE=4 SV=1
MCA_05853_165.848%4071.70e-152MCA_05853_1
A0A060TAR1_BLAAD57.937%3783.15e-133ARAD1B02706p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B02706g PE=4 SV=1
A0A1E3PJL3_9ASCO56.743%3931.98e-131Peptidyl-prolyl cis-trans isomerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82639 PE=4 SV=1
PPID_YARLI54.521%3764.15e-113Peptidyl-prolyl cis-trans isomerase D OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CPR6 PE=3 SV=1
A0A167EPM2_9ASCO51.688%3855.24e-112Peptidylprolyl isomerase CPR6 OS=Sugiyamaella lignohabitans GN=CPR6 PE=4 SV=1
UniRef50_A0A167EPM251.688%3851.44e-108Peptidylprolyl isomerase CPR6 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167EPM2_9ASCO
PPID_CANAL49.072%3779.92e-99Peptidyl-prolyl cis-trans isomerase D OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CPR6 PE=3 SV=2
A0A1E4TKY2_9ASCO49.468%3768.46e-97Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_86310 PE=4 SV=1
PPID_YEAST43.557%3882.65e-75Peptidyl-prolyl cis-trans isomerase CPR6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CPR6 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0377

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Repeat
1 50 100 150 200 250 300 350 389

Detailed signature matches

  1. Domain IPR029000
    Cyclophilin-like domain
    1. SSF50891 (Cyclophil...)
    2. G3DSA:2.40.10...
  2. Domain IPR002130
    Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
    1. PF00160 (Pro_isomerase)
    2. PS50072 (CSA_PPIASE_2)
    3. PR00153 (CSAPPISMRASE)
  3. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
    2. SSF48452 (TPR-like)
  4. Domain IPR013026
    Tetratricopeptide repeat-containing domain
    1. PS50293 (TPR_REGION)
  5. Repeat IPR019734
    Tetratricopeptide repeat
    1. PS50005 (TPR)
    2. SM00028 (tpr_5)
  6. SITE IPR020892
    Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
    1. PS00170 (CSA_PPIASE_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd01926 (cyclophili...)
  2. mobidb-lite (disord...)

Residue annotation

  1. active site cd01926

Protein sequence

>MIA_06375_1
MDIKDLINEPERPRVYLDISIGGKPIGRAIFQLFSDIVPKTAENFRALCTGDRGVGKIGYPLHYKGSKFHRVIKNFMIQG
GDFTVGNGTGGESIYGERFPDEQPLLTSSATTPPTHEPFVLSMANSGPNTNGSQFFITTLATHHLDGKHVVFGRLLAGKS
VVRTIEHTPTGANDKPVQDVVVTDCGELLATAKLEDYIVTDGTGDPYEDFPDDEDSVKTSDDDPGPPLAAAEKIKQIGTT
LLKESNTQDKKLLALAKYRKALRYINEYLPDPDKHPGPYRQFLKLKTALHLNIALVALQVGQFADAQRAANNALDVAGIT
PQERAKALYRRGLALARSKNEESAVLDFEAALKIVPGDAAIVNELARVKQVMQKRREGEKAAYSKFFGK

GO term prediction

Biological Process

GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

Molecular Function

GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding

Cellular Component

None predicted.