MIA_06311_1

Protein

Length

311 amino acids

Protein function

EGGNOG:	0PMCT	AIM18	Altered inheritance of mitochondria protein 18, mitochondrial
SGD closest match:	S000001241	AIM18	Altered inheritance of mitochondria protein 18, mitochondrial
CGD closest match:	CAL0000197659	orf19.6189	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MCA_06314_1	53.546%	282	3.44e-102	MCA_06314_1
A0A0J9XB49_GEOCN	46.984%	315	7.51e-89	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA08s02958g PE=4 SV=1
UniRef50_A0A0J9XB49	46.984%	315	1.54e-85	Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XB49_GEOCN
A0A060SYT4_BLAAD	45.833%	240	2.69e-64	ARAD1A14322p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A14322g PE=4 SV=1
A0A1E3PMK9_9ASCO	47.899%	238	1.92e-62	Chalcone isomerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_69716 PE=4 SV=1
A0A167DH85_9ASCO	44.770%	239	1.45e-57	Aim18p OS=Sugiyamaella lignohabitans GN=AIM18 PE=4 SV=1
Q6C8V2_YARLI	45.701%	221	4.47e-54	YALI0D16775p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D16775g PE=4 SV=1
A0A1D8PKW5_CANAL	39.827%	231	5.53e-48	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6189 PE=4 SV=1
A0A1E4TMI0_9ASCO	34.167%	240	3.64e-33	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_95547 PE=4 SV=1
AIM18_YEAST	34.387%	253	3.35e-31	Altered inheritance of mitochondria protein 18, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AIM18 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9852
Predicted cleavage: 46

Protein family membership

None predicted.

Domains and repeats

Domain
60 - 289
Chalcone isomerase, 3-layer sandwich (IPR016088)
Domain
79 - 310
Chalcone isomerase (IPR016087)

1 50 100 150 200 250 311

Detailed signature matches

IPR016088

Chalcone isomerase, 3-layer sandwich
1. G3DSA:3.50.70.10
  
  60 - 289
  
  GENE3D
  G3DSA:3.50.70.10 (G3DSA:3.50.70.10)
IPR016087

Chalcone isomerase
1. SSF54626 (Chalcone ...)
  
  79 - 310
  
  SUPERFAMILY
  SSF54626 (Chalcone isomerase)
2. PF16035 (Chalcone_2)
  
  97 - 304
  
  Pfam
  PF16035 (Chalcone_2)

no IPR

Unintegrated signatures

NON_CYTOPLASM... (N...)

39 - 311

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 38

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

35 - 38

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

24 - 34

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 23

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)

Protein sequence

>MIA_06311_1
MSFAFRRIFRPSNVFNIFKKPSRLLPGTCLSLGLGAYAFHQYNRKAVLLDSPTQGAPNPKAVLVSDEQGKLFVQPQTKCP
PFPSTISLPDSQSPNSSYELLGVGVRTVSFLSFHVYAVGIYIAKNDIQLAHSILKFAANNLSSGDLKEALLDPNTSTKVI
SHLLDHGIRFDIRIVPVRNTDFSHLRDGFVRGVLNHPHYKELINHPAISMSDPAHIKLIDEMGQGVNQLKVAFSRKMSVP
KYNLIHLVHDSNASLKISYIAAQSEDPAKETVLGTVDDPNVSKILVLHYLTGKHPASESARSNAIDGLVSL

GO term prediction

Biological Process

GO:0009813 flavonoid biosynthetic process

Molecular Function

GO:0016872 intramolecular lyase activity
GO:0045430 chalcone isomerase activity

Cellular Component