Protein

MIA_06114_1

Length
561 amino acids

Browser: contig10:293833-295519+

Protein function

EGGNOG:0PFY3FG08700.1malate synthase
SGD closest match:S000001470DAL7Malate synthase 2, glyoxysomal
CGD closest match:CAL0000178842MLS1Malate synthase

Protein alignments

%idAln lengthE-value
A0A0J9XD51_GEOCN76.545%5500.0Malate synthase OS=Geotrichum candidum GN=BN980_GECA10s02518g PE=3 SV=1
A0A1E3PCX7_9ASCO70.620%5480.0Malate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84450 PE=3 SV=1
A0A167C5Z1_9ASCO65.392%5490.0Malate synthase OS=Sugiyamaella lignohabitans GN=MLS1 PE=3 SV=1
UniRef50_A3LZ1062.522%5630.0Malate synthase n=14 Tax=Fungi TaxID=4751 RepID=A3LZ10_PICST
Q6C5R9_YARLI64.381%5250.0Malate synthase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E15708g PE=3 SV=2
MCA_02473_165.019%5260.0MCA_02473_1
A0A060T493_BLAAD62.044%5480.0Malate synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B01386g PE=3 SV=1
A0A1E4TAJ2_9ASCO64.943%5220.0Malate synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57888 PE=3 SV=1
MASZ_YEAST62.684%5440.0Malate synthase 2, glyoxysomal OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAL7 PE=1 SV=2
Q5APD2_CANAL56.466%5490.0Malate synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MLS1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0252

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 561

Detailed signature matches

  1. Family IPR001465
    Malate synthase
    1. PF01274 (Malate_syn...)
  2. Family IPR006252
    Malate synthase A
    1. cd00727 (malate_synt_A)
    2. TIGR01344
    3. PIRSF001363 (Malate...)
  3. Domain IPR011076
    Malate synthase-like
    1. SSF51645 (Malate sy...)
  4. SITE IPR019830
    Malate synthase, conserved site
    1. PS00510 (MALATE_SYN...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.20.12...
  2. G3DSA:3.20.20...

Residue annotation

  1. active site cd00727

Protein sequence

>MIA_06114_1
MPSVKIVAELDSSSPYPSGTTPQDILTKGALEFVVSLHRTFNNRRKKLLETRVKRQTEIDAGKLPSFLEETKHIREDIAW
QGPVPAPGLVDRRVEITGPPDRKMIVNAFNSNVTTYMTDFEDSMAPTWTNVIWGQANLYDAVRGKLDFVAKDTGKEYKVK
EASTHFNGKLPTLIVRPRGWHMVEKHIVVDGEPISASIFDFGVFFYHNAKALIAKGHGPYFYLPKMEAYQEARLWNDIFN
VAQDTLEIPRGTIRATVLIETLTGAFELEEIIYELRQHSSGLNCGRWDYMFSTIKKLRHYKDKVLPDRGDVTMTVPFMAA
YVKYLIEVCHKRGVHAMGGMAAQIPIKGDEAANAAAMERVKADKLREATAGHDGTWVAHPALARIATDIFGEYMPHPNQL
FYRPELDNEGYLPVETGDLLNTQITGGKITEAGIRKNIYIGLNYMEAWLRGVGCVPIDWLMEDAATAEVSRAQLNQWVLH
GVKTEDTGKVITAELNKAILAEETSKLLAGAKEGNKFELAAKYFLPEITGEKFSDFLTTLLYDELTAGESYGEISAEALK
A

GO term prediction

Biological Process

GO:0006097 glyoxylate cycle

Molecular Function

GO:0003824 catalytic activity
GO:0004474 malate synthase activity

Cellular Component

None predicted.