Protein

MIA_06086_1

Length
308 amino acids


Browser: contig10:182539-183531-

Protein function

EGGNOG:0PFVXPGUG_03867mitochondrial peroxiredoxin Prx1
SGD closest match:S000000160PRX1Mitochondrial peroxiredoxin PRX1
CGD closest match:CAL0000196398PRX1Thioredoxin peroxidase

Protein alignments

%idAln lengthE-value
A0A0J9XA47_GEOCN75.191%2623.42e-145Similar to Saccharomyces cerevisiae YBL064C PRX1 Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides OS=Geotrichum candidum GN=BN980_GECA05s05202g PE=4 SV=1
A0A060T3K8_BLAAD71.795%2349.86e-128ARAD1C38082p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38082g PE=4 SV=1
A0A1E3PNK9_9ASCO72.768%2244.70e-123Thioredoxin-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81635 PE=4 SV=1
A0A167CJS0_9ASCO70.925%2275.61e-120Prx1p OS=Sugiyamaella lignohabitans GN=PRX1 PE=4 SV=1
Q6C2G0_YARLI70.306%2291.59e-120YALI0F08195p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F08195g PE=4 SV=1
PRX1_YEAST65.000%2201.98e-105Mitochondrial peroxiredoxin PRX1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRX1 PE=1 SV=1
UniRef50_P3422765.000%2204.73e-102Mitochondrial peroxiredoxin PRX1 n=31 Tax=saccharomyceta TaxID=716545 RepID=PRX1_YEAST
A0A1E4TB15_9ASCO55.512%2549.46e-97Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58020 PE=4 SV=1
Q5A5A0_CANAL55.947%2277.13e-90Thioredoxin peroxidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRX1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9926
Predicted cleavage: 39

Protein family membership

None predicted.

Domains and repeats

1 50 100 150 200 250 308

Detailed signature matches

    1. SSF52833 (Thioredox...)
    1. PS51352 (THIOREDOXIN_2)
    1. PF00578 (AhpC-TSA)
    1. PF10417 (1-cysPrx_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDS00024 (Peroxir...)
  2. cd03016 (PRX_1cys)

Residue annotation

  1. dimer interface cd...
  2. decamer (pentamer ...
  3. SFLDS00024
  4. catalytic triad cd...

Protein sequence

>MIA_06086_1
MSAILRRSIATVSRSQLRATSSCVSQPSRALGFRFSSTFKQEDQPRIRIGSEAPNFKAVTTQGEINFHEWIGDSWAVLFS
HPADFTPVCTTELGAFSQLAPEFAKRNTKLIGLSADPLEDHVKWIKDIEDVATNGSPFQFPVIADVDRNVSFLYDMVDQA
NFEKLDKGIAFTIRNVFIIDPSKKVRLFLVYPASTGRNTAEVLRVLDALQLTDKAGVVTPANWAQGQDVIIPPSVSNADA
KAKFGDFKEVKPYLRFTKEPTVKSSFAGSSAGPLAGFIVAAAAGAFALTQVDDKDQAKVAQLKGVFEK

GO term prediction

Biological Process

GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0051920 peroxiredoxin activity

Cellular Component

None predicted.