Protein
MIA_05991_1
Length
728 amino acids
Browser: contig09:915044-917401+
Protein function
| EGGNOG: | 0PNTX | RGT1 | Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose. In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator. In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription |
|---|---|---|---|
| SGD closest match: | S000001521 | RGT1 | Glucose transport transcription regulator RGT1 |
| CGD closest match: | CAL0000176948 | RGT1 | Rgt1p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9YHN8_GEOCN | 28.111% | 651 | 7.12e-38 | Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA01s07149g PE=4 SV=1 |
| MCA_05290_1 | 58.586% | 99 | 1.02e-26 | MCA_05290_1 |
| UniRef50_A0A0J9X9E9 | 66.667% | 66 | 1.07e-19 | Similar to Saccharomyces cerevisiae YKL038W RGT1 Glucose-responsive transcription factor n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9E9_GEOCN |
| A0A167F2V1_9ASCO | 28.152% | 341 | 2.79e-21 | Transcription factor (Predicted) OS=Sugiyamaella lignohabitans GN=adn3 PE=4 SV=1 |
| A0A1E3PJ62_9ASCO | 65.672% | 67 | 1.85e-20 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52059 PE=4 SV=1 |
| A0A1E4TBQ7_9ASCO | 58.571% | 70 | 3.23e-20 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32521 PE=4 SV=1 |
| A0A060TEP2_BLAAD | 55.000% | 80 | 1.14e-18 | ARAD1D09372p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09372g PE=4 SV=1 |
| RGT1_YEAST | 62.500% | 56 | 8.94e-16 | Glucose transport transcription regulator RGT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RGT1 PE=1 SV=1 |
| A0A1D8PLL4_CANAL | 57.576% | 66 | 9.99e-16 | Rgt1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RGT1 PE=4 SV=1 |
| Q6C1G1_YARLI | 40.000% | 50 | 7.97e-07 | YALI0F16599p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F16599g PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1150
Predicted cleavage: 35
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
728
Detailed signature matches
no IPR
Unintegrated signatures
-
cd12148 (fungal_TF_MHR)
-
mobidb-lite (disord...)
Residue annotation
-
DNA binding site c...
-
Zn2+ binding site ...
Protein sequence
>MIA_05991_1 MSSGFVPVVGSAPKTETPPHPRKQSPSAMPRKRSKVSRACDACRKKKIRCDSNPDDEGRLQCSSCKKAGIECCFYRVPLK RGPSKGQRKDLQPSSSSSPDKTPLPPSLRSPAIKPSSSPPPPTGNFRKRSFSITCAALAHNNIPADSHSLLPPKPQQLSP ESPSLPSITNFFNLKSLSKPRVHSPPPSSIHQLHAHSFLLHQPPLRGPALSFPPHTSAKSPPPTALTAPKSSGPLQNCSE LDLQHLRKNTHQTSSPNLPNKSGSVSRSNSVPNYLPSTDDPQHPPSSPPNKLRKLAIPSPQSLLTAHWNDLAIDSYYHLV HPVIPILPPSKVRLQAWLQTTASCPESTSLAIAILTGVSALYSTFSHHHPTPSPQILPAISTILALPQSHPSRASPAFVV LLIIQHLLTQNDSIWLSMAISVAYQLNMHLPKSLAPPLVTPKHRYDDDDDDDDDNLPLSSDTDTSDDDYYLSSRSSSLSS IQESLHKRLFHVLVLLDAMHSSLAKVPGFIPASLVYAADSDPVARVCVLFKRALDISPSSSPGLQADLYRTRLSLERSWD TAPSLKGLYLCAEITAAAAAATSSATSALHPTDPLADSLASLVGLLGSPLMGVSPLAPFFAQTAASHLCALAATVPATTS PGTILLGNRVAALLTSLLDTRGNMLDATLRQRACNTLSTLRKQSASPPGPQEAAPRDARYSEIRSPSPLSTSSALDRLAS LAEKVQVV
GO term prediction
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Molecular Function
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270 zinc ion binding
Cellular Component
GO:0005634 nucleus