MIA_05700_1

Protein

Length

574 amino acids

Protein function

EGGNOG:	0QDJB	PGUG_05050	transporter
SGD closest match:	S000001428	YIL166C	Uncharacterized transporter YIL166C
CGD closest match:	CAL0000201100	orf19.6520	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
A0A0J9YHM4_GEOCN	63.103%	580	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA01s06654g PE=4 SV=1
A0A167D9I1_9ASCO	61.252%	511	0.0	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_906 PE=4 SV=1
A0A1E3PQH2_9ASCO	55.749%	574	0.0	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_19598 PE=4 SV=1
UniRef50_A3LWD0	61.144%	507	0.0	Putative allantoate permease n=276 Tax=Dikarya TaxID=451864 RepID=A3LWD0_PICST
A0A1D8PQZ7_CANAL	60.355%	507	0.0	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6520 PE=4 SV=1
Q6CDV0_YARLI	58.252%	515	0.0	YALI0B21010p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B21010g PE=4 SV=1
A0A060T3B5_BLAAD	54.951%	515	0.0	ARAD1C35992p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35992g PE=4 SV=1
YIQ6_YEAST	46.078%	510	8.28e-167	Uncharacterized transporter YIL166C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YIL166C PE=1 SV=1
A0A1E4TFX3_9ASCO	27.329%	483	1.38e-47	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2334 PE=4 SV=1
MCA_01039_1	22.876%	459	4.01e-40	MCA_01039_1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0038

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
93 - 542
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 574

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  122 - 497
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  93 - 542
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  115 - 498
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

1 - 113

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

173 - 209

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

537 - 574

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

470 - 480

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

378 - 418

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

264 - 274

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

336 - 567

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

101 - 304

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

231 - 241

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

504 - 514

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

296 - 354

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

439 - 449

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

133 - 151

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

211 - 230

TMHMM
TMhelix (TMhelix)

483 - 500

TMHMM
TMhelix (TMhelix)

515 - 537

TMHMM
TMhelix (TMhelix)

448 - 470

TMHMM
TMhelix (TMhelix)

240 - 262

TMHMM
TMhelix (TMhelix)

275 - 297

TMHMM
TMhelix (TMhelix)

355 - 377

TMHMM
TMhelix (TMhelix)

419 - 438

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

275 - 295

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

515 - 536

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

419 - 438

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

152 - 172

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

242 - 263

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

210 - 230

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

450 - 469

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

481 - 503

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

355 - 377

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

114 - 132

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

1 - 35

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

129R

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

132I

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

133T

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

134Q

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

136L

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

137S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

155M

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

158F

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

159Y

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

162F

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

166E

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

167L

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

169S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

170Q

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

216E

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

217G

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

220I

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

221A

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

224V

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

225S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

228T

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

240L

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

241S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

244Y

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

245S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

251Q

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

365Y

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

368M

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

369S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

372S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

373A

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

376T

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

389T

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

393T

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

397N

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

400H

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

404L

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

456L

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

459P

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

460Y

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

463A

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

467G

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

468L

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

471R

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

482S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

483S

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

486Y

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

487N

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

490C

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

491Q

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

494L

putative substrate translocation pore
129R, 132I, 133T, 134Q, 136L, 137S, 155M, 158F, 159Y, 162F, 166E, 167L, 169S, 170Q, 216E, 217G, 220I, 221A, 224V, 225S, 228T, 240L, 241S, 244Y, 245S, 251Q, 365Y, 368M, 369S, 372S, 373A, 376T, 389T, 393T, 397N, 400H, 404L, 456L, 459P, 460Y, 463A, 467G, 468L, 471R, 482S, 483S, 486Y, 487N, 490C, 491Q, 494L
CDD
cd06174 (MFS)

Protein sequence

>MIA_05700_1
MSYDKEKKEEDYTLTTKQVGGANSDDEFSSPKKSKSIDPYLLTEEEYEIESGTKKGRHKFYGGKDHVFRDPAVADYYREV
YEKSTYEGRNHFDPDFTWTPEQERKVLWKIEFRACFWACVMFLGLQLDRGNITQALSDNMLKDLGMTTNDYNTGMTIFYV
VFLFAELPSQLISKKLGPDRWIPAQITLWSIVSACQSKITGKSSFYATRALLGLLEGGFIADTVSWLTYFYTGSELPIRL
SFFYSALTLTQIGASLLAFGVLRMRGIGGWAGWRWLFLLEGLFTLIIGILSFFQLPPSAVQTKTWFRPKGWFTEFEEKLI
VNRVLRDDPSKGDMHNRQAISFRGLYDSLMDYDVWPIYASGLVAYIPMSTVSAYLTLTLKQLGFSTFNTNLLTIPPNVAH
LGLLFFQTWLTEHFNERTLLCTFQPLWLIICAGVLAFWKDSLKNVWGTYAILVIYLASPYIHAVLIGLLSRNSNTVRTRN
VSSAVYNMFCQVSLIIASNIYRADDKPYYRRGNRVLFALGWVSLAILIFTKVYYVWRNKSRDKIWDAMTIEEQHEYRRTT
KDKGNKRLDFRFTH

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features