Protein

MIA_05675_1

Length
404 amino acids

Browser: contig09:39769-40984+

Protein function

EGGNOG:0PGYKFG01177.1Cystathionine gamma-lyase
SGD closest match:S000000010CYS3Cystathionine gamma-lyase
CGD closest match:CAL0000178125CYS3Cystathionine gamma-lyase

Protein alignments

%idAln lengthE-value
MCA_05818_184.461%3990.0MCA_05818_1
A0A0J9XDQ8_GEOCN83.582%4020.0Similar to Saccharomyces cerevisiae YAL012W CYS3 Cystathionine gamma-lyase OS=Geotrichum candidum GN=BN980_GECA09s02639g PE=3 SV=1
A0A167FXE2_9ASCO73.418%3950.0Cystathionine gamma-lyase CYS3 OS=Sugiyamaella lignohabitans GN=CYS3 PE=3 SV=1
A0A1E3PN83_9ASCO72.457%4030.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50656 PE=3 SV=1
Q6C2Q9_YARLI71.212%3960.0YALI0F05874p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F05874g PE=3 SV=1
A0A060TFQ7_BLAAD69.697%3960.0ARAD1D25014p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D25014g PE=3 SV=1
Q5A362_CANAL66.667%4050.0Cystathionine gamma-lyase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CYS3 PE=3 SV=1
CYS3_YEAST64.516%4030.0Cystathionine gamma-lyase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CYS3 PE=1 SV=2
UniRef50_P3137364.516%4031.63e-180Cystathionine gamma-lyase n=350 Tax=Fungi TaxID=4751 RepID=CYS3_YEAST
A0A1E4TGW9_9ASCO64.428%4020.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_113949 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0568

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 404

Detailed signature matches

  1. Family IPR000277
    Cys/Met metabolism, pyridoxal phosphate-dependent enzyme
    1. cd00614 (CGS_like)
    2. PIRSF001434 (CGS)
    3. PF01053 (Cys_Met_Me...)
  2. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...
  3. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  4. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...

Residue annotation

  1. homodimer interfac...
  2. pyridoxal 5'-phosp...
  3. substrate-cofactor...
  4. catalytic residue ...

Protein sequence

>MIA_05675_1
MTVSNTSNFATLAVHAGSQADAATGAVIPAISLSTTFAQSKPAVPLGEYEYSRSANPNRDGFETAIAALEGAKYALAYSS
GSAATANVLQALASNTHLVSIGDVYGGTHRYFTKVAHAHSVDVAFTNLIEHELEQALTPQTSLVWIESPSNPTLTVTDIS
VVAGIIARERAARAAASSTPNPIYLVVDNTFLSPYIQNPLAHGADVVVHSVTKYINGHSDVVMGVAATSNDTIHEKLRFL
QNALGAIPSPFDSWLAHRGLKTLHLRARAASSNALAVAQYLENAIGSTVVAVSYPGLKSHPKRDVVLKQHRDGLGGGMVS
FRINGGAEAANKFCASTKIFTLAESLGGIESLCEVPAQMTHAGIPKDKREASGVYDDLIRLSVGIEDSEDILADIEQALA
KATA

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.