Protein

MIA_05625_1

Length
831 amino acids

Browser: contig08:953944-956485-

Protein function

EGGNOG:0PFR6PGUG_01964DNA mismatch repair protein
SGD closest match:S000005026PMS1DNA mismatch repair protein PMS1
CGD closest match:CAL0000197853PMS1ATP-binding mismatch repair protein

Protein alignments

%idAln lengthE-value
MCA_00758_157.920%4236.78e-163MCA_00758_1
A0A0J9XFW8_GEOCN57.326%3895.37e-146Similar to Saccharomyces cerevisiae YNL082W PMS1 ATP-binding protein required for mismatch repair in mitosis and meiosis OS=Geotrichum candidum GN=BN980_GECA12s02287g PE=4 SV=1
UniRef50_A0A0J9XFW857.326%3891.10e-142Similar to Saccharomyces cerevisiae YNL082W PMS1 ATP-binding protein required for mismatch repair in mitosis and meiosis n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XFW8_GEOCN
A0A1E3PGR0_9ASCO50.132%3796.42e-124DNA mismatch repair protein MutL OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53089 PE=4 SV=1
A0A060T8K1_BLAAD48.438%3846.69e-119ARAD1D12122p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D12122g PE=4 SV=1
A0A167FC59_9ASCO49.725%3643.99e-109Pms1p OS=Sugiyamaella lignohabitans GN=PMS1 PE=4 SV=1
PMS1_YEAST42.308%3644.25e-88DNA mismatch repair protein PMS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMS1 PE=1 SV=3
Q6C6B8_YARLI41.240%3712.19e-85YALI0E10769p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E10769g PE=4 SV=1
A0A1E4TJ67_9ASCO45.489%2667.53e-67Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30112 PE=4 SV=1
A0A1D8PII6_CANAL36.236%3561.96e-62ATP-binding mismatch repair protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMS1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1331

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 831

Detailed signature matches

  1. Family IPR002099
    DNA mismatch repair protein family
    1. TIGR00585
  2. Domain IPR003594
    Histidine kinase-like ATPase, C-terminal domain
    1. G3DSA:3.30.56...
    2. SSF55874 (ATPase do...)
  3. Domain IPR020568
    Ribosomal protein S5 domain 2-type fold
    1. SSF54211 (Ribosomal...)
  4. Domain IPR014721
    Ribosomal protein S5 domain 2-type fold, subgroup
    1. G3DSA:3.30.23...
  5. Domain IPR013507
    DNA mismatch repair protein, C-terminal
    1. SM01340 (DNA_mis_re...)
    2. PF01119 (DNA_mis_re...)
  6. Domain IPR014790
    MutL, C-terminal, dimerisation
    1. SM00853 (MutL_C_2)
    2. PF08676 (MutL_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. PF13589 (HATPase_c_3)
  3. SSF118116 (DNA mism...)
  4. cd00075 (HATPase_c)
  5. cd03484 (MutL_Trans...)

Residue annotation

  1. ATP binding site c...
  2. Mg2+ binding site ...
  3. G-X-G motif cd00075
  4. ATP binding site c...

Protein sequence

>MIA_05625_1
MTGGIEIINSNLIHSITSGQVIIDLASSVKELVENAVDAHASVVEVRFKNHGVDSLEVIDDGDGIAKNDFIGLGRKHYTS
KLRSYDDLLLVQTLGFRGEAINSLCSLAKVEVITSTVNDIPLATKLLFDSTGEIISKTETSGKKGTHVIVCNLFESLPVR
RKDFLKNFKREFSKAISLLQAYAVICTDVKIIVSNTSGPSNKKTVLFSTTGKGGLKSSVANIFGVSIFEKLIPINLSFTL
FYSFPRSLKKPETSLNDESATVEIEGFISKPIFGNGRSASDRQLYFINSRPCSLPQIAKAINETYKVFNNTQLPVVVANI
KLDTTRYDINVSPDKRTILLHNESGLIELVRENFSELFEKVGHSVPLNKVDTVITATKINQNALFCSNHRELEKDEEIQI
NNFNKTSAFKQKYDRLDQDNVLISNEESLSRIRSNERNNDDLTIRNNDIDEEVINNDDNKQHLKTATRPSKTSDQTLVDL
PHQCSPKDCFHGYSEECVTEFNSKEKEEKRHFSNSSVQAETFKFNEATSSSFQTVSRSGSQRNRTYNYDISLRVSKNQIG
ICKKELLRLQKIRNKGYIRASDRLKINNQNSEKHLSSITISDISENTEIAESMLDMTIHKKDFLNMEVIGQFNLGFILVT
NYNEDNHRKDLFIVDQHASDEIYNFERLQRETTIKTQPLISPLPLELTVMEEITLMSNLTVFDDNGFKVKIDENAPPGHK
CQLIALPTSKSTKFDTKDLQELIYILETQPGKKNIRCSKLRAMYAMRACRSSIMIGKPLNRLIMERVVRNLSALDKPWNC
PHGRPTMRHLVSLSQFYGSYDDYLKISSLSQ

GO term prediction

Biological Process

GO:0006298 mismatch repair

Molecular Function

GO:0005524 ATP binding
GO:0030983 mismatched DNA binding

Cellular Component

None predicted.