Protein

MIA_05617_1

Length
403 amino acids

Browser: contig08:934716-935984+

Protein function

EGGNOG:0PFD6FG07436.1tyrosyl-tRNA synthetase
SGD closest match:S000003417TYS1Tyrosine--tRNA ligase, cytoplasmic
CGD closest match:CAL0000188062TYS1Tyrosine--tRNA ligase

Protein alignments

%idAln lengthE-value
MCA_02023_183.243%3700.0MCA_02023_1
A0A0J9XDD4_GEOCN77.748%3730.0Tyrosine--tRNA ligase OS=Geotrichum candidum GN=BN980_GECA10s02562g PE=3 SV=1
A0A161HHJ8_9ASCO77.089%3710.0Tyrosine--tRNA ligase OS=Sugiyamaella lignohabitans GN=TYS1 PE=3 SV=1
A0A060TC84_BLAAD70.574%4010.0Tyrosine--tRNA ligase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B14762g PE=3 SV=1
A0A1E3PMD0_9ASCO73.699%3460.0Tyrosine--tRNA ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50516 PE=3 SV=1
SYYC_YEAST71.543%3760.0Tyrosine--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TYS1 PE=1 SV=3
UniRef50_P3642171.543%3760.0Tyrosine--tRNA ligase, cytoplasmic n=22 Tax=Opisthokonta TaxID=33154 RepID=SYYC_YEAST
Q5AFB3_CANAL69.947%3760.0Tyrosine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TYS1 PE=3 SV=1
Q6CBV3_YARLI68.901%3735.51e-178Tyrosine--tRNA ligase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C15224g PE=3 SV=1
A0A1E4THQ3_9ASCO65.306%3437.72e-173Tyrosine--tRNA ligase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57525 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1042

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 403

Detailed signature matches

  1. Family IPR002305
    Aminoacyl-tRNA synthetase, class Ic
    1. PF00579 (tRNA-synt_1b)
  2. Family IPR002307
    Tyrosine-tRNA ligase
    1. TIGR00234
    2. cd00805 (TyrRS_core)
    3. PR01040 (TRNASYNTHTYR)
  3. Family IPR023617
    Tyrosine-tRNA ligase, archaeal/eukaryotic-type
    1. PIRSF006588 (TyrRS_...)
  4. Domain IPR014729
    Rossmann-like alpha/beta/alpha sandwich fold
    1. G3DSA:3.40.50...
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.24...
  2. SSF52374 (Nucleotid...)
  3. mobidb-lite (disord...)

Residue annotation

  1. active site cd00805
  2. HIGH motif cd00805
  3. dimer interface cd...
  4. KMSKS motif cd00805

Protein sequence

>MIA_05617_1
MATDLSPQEKYDLITKNLQEVLNGQIIKNVLEVENRPLKIYWGTAPTGRPHCGYFVPMTKIAHFLKAGAEVTVLLADLHA
FLDNMKAPLELVEFRSQYYERIVKTILSSIGVPIEKLKFTIGRSYQLNGDYTLDIFRMANVVSQNDAKRAGADVVKQVSN
PLLSGLIYPIMQALDEQYLDVDAQFGGLDQRKIFVLAEEQLPTIGYKKRAHLMNPMVPGLTQGGKMSASDPNSKIDLLEE
PKQVKKKIGSAFAAPGIVEGNGLISFVEYVVLPISEISTGKPLFHINRPDQYGGPLNYSTIDELKQDYESQKLSPQDLKI
GVTDAINALLEPIRKAFESDAEFQELEKKAYPPPEKAKKTKKVKKIGTRYPGAKPEQSDSSAPSSSSKSEIEKVGETLKE
ASI

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm