Protein

MIA_05476_1

Length
380 amino acids

Browser: contig08:586277-587420-

Protein function

EGGNOG:0PG9Nalcohol dehydrogenase
SGD closest match:S000004918ADH2Alcohol dehydrogenase 2
CGD closest match:CAL0000176391orf19.4287Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_02119_159.103%3793.81e-156MCA_02119_1
UniRef50_Q4WFK055.914%3724.81e-136Zinc-containing alcohol dehydrogenase, putative n=31 Tax=leotiomyceta TaxID=716546 RepID=Q4WFK0_ASPFU
A0A1E4TD51_9ASCO53.226%3722.97e-129Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32873 PE=3 SV=1
A0A060T3G6_BLAAD50.949%3695.79e-125ARAD1A09592p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A09592g PE=3 SV=1
A0A1D8PNH7_CANAL41.019%3733.06e-97Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4287 PE=3 SV=1
A0A167EJW3_9ASCO28.818%4065.88e-43Bifunctional alcohol dehydrogenase/S-(Hydroxymethyl)glutathione dehydrogenase OS=Sugiyamaella lignohabitans GN=SFA1 PE=3 SV=1
A0A1E3PFP5_9ASCO28.537%4178.96e-35GroES-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47408 PE=4 SV=1
A0A0J9XJK3_GEOCN31.596%3071.15e-18Similar to Saccharomyces cerevisiae YMR083W ADH3 Mitochondrial alcohol dehydrogenase isozyme III OS=Geotrichum candidum GN=BN980_GECA19s01275g PE=3 SV=1
ADH2_YEAST27.961%3041.73e-18Alcohol dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH2 PE=1 SV=3
Q6C648_YARLI26.963%3823.64e-17YALI0E12463p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E12463g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0164
Predicted cleavage: 30

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 380

Detailed signature matches

  1. Domain IPR011032
    GroES-like
    1. SSF50129 (GroES-like)
  2. Domain IPR013154
    Alcohol dehydrogenase, N-terminal
    1. PF08240 (ADH_N)
  3. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  4. Domain IPR013149
    Alcohol dehydrogenase, C-terminal
    1. PF00107 (ADH_zinc_N)
  5. SITE IPR002328
    Alcohol dehydrogenase, zinc-type, conserved site
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. G3DSA:3.90.18...
  3. cd08284 (FDH_like_2)

Residue annotation

  1. catalytic Zn bindi...
  2. NAD(P) binding sit...
  3. structural Zn bind...

Protein sequence

>MIA_05476_1
MTPIHPELPKTMAAVVFNGPHNISLETRPVPALSSPGSVLLRVNYTALCGSELHVFRGNQPSPTDFIMGHEFTGTVVRVG
PDVHAFAIGDNVVSPFTISCGSNCFYCRHGASSRCTQSRLFGTAALDGGQAEYVEVPLADSTLVKQPHLRPGVDPVAAEK
KLVLMADIFPTGYFAATNAFKDAYFTATPASARPETPKDPQDGPFVAVVVGCGPVGLCAIAAAKYLLPPDAILYAIDSVP
ARLDLAKALGAIPLPLDQDPVATIKKASQGRGADAVMEIVGHAAALRIAFDAVRPWGRIASVGVHNEDIPITGNEAYGKN
VTIQFGRCPVRSIFDDALKVFVAVMDKLDFLTGTVVKLADAKEAYDLFDQHKVEKVIFQI

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.