MIA_05431_1

Protein

Length

336 amino acids

Browser: contig08:442060-443071-

Protein function

EGGNOG:	0PI59	MXR1	peptide methionine sulfoxide reductase
SGD closest match:	S000000844	MXR1	Peptide methionine sulfoxide reductase
CGD closest match:	CAL0000176448	MXR1	Peptide-methionine-S-sulfoxide reductase

Protein alignments

	%id	Aln length	E-value
MCA_01658_1	63.366%	202	4.32e-94	MCA_01658_1
A0A0J9X2X2_GEOCN	58.294%	211	1.45e-81	Similar to Saccharomyces cerevisiae YER042W MXR1 Methionine-S-sulfoxide reductase OS=Geotrichum candidum GN=BN980_GECA01s11395g PE=3 SV=1
A0A060TCJ8_BLAAD	56.000%	200	1.15e-80	ARAD1D43032p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D43032g PE=3 SV=1
A0A161HIX0_9ASCO	57.143%	203	3.95e-77	Mxr1p OS=Sugiyamaella lignohabitans GN=MXR1 PE=3 SV=1
A0A1E3PK07_9ASCO	55.721%	201	2.59e-73	Methionine sulfoxide reductase A OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50924 PE=3 SV=1
A0A1E4TH58_9ASCO	54.040%	198	7.71e-71	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57447 PE=3 SV=1
Q6C588_YARLI	52.764%	199	2.60e-68	YALI0E20119p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E20119g PE=3 SV=1
UniRef50_A0A0L1HDC1	50.510%	196	3.22e-62	Peptide methionine sulfoxide reductase n=17 Tax=saccharomyceta TaxID=716545 RepID=A0A0L1HDC1_9PLEO
Q5AD39_CANAL	45.050%	202	2.04e-56	Peptide-methionine-S-sulfoxide reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MXR1 PE=3 SV=1
MSRA_YEAST	45.500%	200	3.06e-54	Peptide methionine sulfoxide reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MXR1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0856

Protein family membership

None predicted.

Domains and repeats

Domain
128 - 332
Peptide methionine sulphoxide reductase MsrA (IPR002569)

1 50 100 150 200 250 300 336

Detailed signature matches

IPR002569

Peptide methionine sulphoxide reductase MsrA
1. MF_01401 (MsrA)
  
  141 - 324
  
  HAMAP
  MF_01401 (MsrA)
2. SSF55068 (Peptide m...)
  
  132 - 320
  
  SUPERFAMILY
  SSF55068 (Peptide methionine sulfoxide reductase)
3. TIGR00401
  
  174 - 317
  
  TIGRFAMs
  TIGR00401 (TIGR00401)
4. G3DSA:3.30.10...
  
  128 - 332
  
  GENE3D
  G3DSA:3.30.1060.10 (G3DSA:3.30.1060.10)
5. PF01625 (PMSR)
  
  144 - 318
  
  Pfam
  PF01625 (PMSR)

no IPR

Unintegrated signatures

NON_CYTOPLASM... (N...)

56 - 336

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 55

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

51 - 55

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

40 - 50

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 39

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
TMhelix

37 - 59

TMHMM
TMhelix (TMhelix)

Protein sequence

>MIA_05431_1
MATKKPSVLKEKPARILKYKKKKSKSTPSWSFENSSSYYTLLIFALSFVFASVMASLLGNKGVAAQQINVDLSQPSSLDP
PTTAFDIKEPQESVVSVELPAESLSDNEAATPEELVEDDHKIKTNYKPTTISPTLNVPQNAQVATFAAGCFWGVEHIFRR
YFAASFLANDSSLNKDFVKRGGLIDAKVGYSGGKNASVYPSYKQVCTNTTGHAEVLQISFDPQIVSYADLVDFFFRIHDP
TTLNQQGPDDFGEQYRSAIFYHNEEQHKIAQDILNKYQHSWYDPAHLKIVTKVEPIKVFWDAELYHQLYLKNNPEGYMCP
SHHLRTEPPLPKKDEL

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008113 peptide-methionine (S)-S-oxide reductase activity

Cellular Component