Protein

MIA_05413_1

Length
519 amino acids

Browser: contig08:384239-385799+

Protein function

EGGNOG:0PK2HNDH51NADH-ubiquinone oxidoreductase 51 kDa subunit
CGD closest match:CAL0000186277NDH51NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

Protein alignments

%idAln lengthE-value
MCA_04987_186.705%5190.0MCA_04987_1
A0A0J9X8N6_GEOCN87.342%4740.0NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Geotrichum candidum GN=BN980_GECA04s04729g PE=3 SV=1
A0A167E5E7_9ASCO86.250%4800.0NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Sugiyamaella lignohabitans GN=AWJ20_1959 PE=3 SV=1
A0A060T3L3_BLAAD85.654%4740.0NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A16786g PE=3 SV=1
F2Z660_YARLI83.898%4720.0NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B20372g PE=3 SV=1
A0A1E4TEH3_9ASCO82.911%4740.0NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_101698 PE=3 SV=1
Q59TD5_CANAL81.264%4590.0NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NDH51 PE=3 SV=1
UniRef50_A0A0J8RVV878.118%4570.0NADH-ubiquinone oxidoreductase 51 kDa subunit n=4 Tax=Coccidioides immitis TaxID=5501 RepID=A0A0J8RVV8_COCIT

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9941
Predicted cleavage: 58

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 519

Detailed signature matches

  1. Family IPR011537
    NADH ubiquinone oxidoreductase, F subunit
    1. TIGR01959
  2. Domain IPR011538
    NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain
    1. PF01512 (Complex1_51K)
  3. Domain IPR019554
    Soluble ligand binding domain
    1. PF10531 (SLBB)
  4. Domain IPR019575
    NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain
    1. PF10589 (NADH_4Fe-4S)
    2. SM00928 (NADH_4Fe_4S_2)
  5. SITE IPR001949
    NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site
    1. PS00644 (COMPLEX1_5...)
    2. PS00645 (COMPLEX1_5...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF140490 (Nqo1C-te...)
  2. SSF142019 (Nqo1 FMN...)
  3. SSF142984 (Nqo1 mid...)
  4. mobidb-lite (disord...)

Protein sequence

>MIA_05413_1
MIASRQLGVVGKSSMARPIPTIYRSISTSSSITQTARPLSNTHQTQRRSLATVVGDNPKPKKHGGLRDQDRIFQNIYSNY
GHDLKSAKRMGDWYKTKEIVLKGHEWIIAEMKKSGLRGRGGAGFPSGLKWSFMNPPGWEKNVGPRYLVVNADEGEPGTCK
DREIIRKDPHKLVEGCLLAGRAMNATAAYIYIRGEFYNEAAILQTAINEAYADGLIGKNACGSGYDFDVYIHRGMGAYVC
GEETALIESLEGKAGKPRLKPPFPAGVGLFGRPTTVTNVETVAVAPTILRRGGDWFASFGRERNSGTKLFCISGHVNEPC
TVEEEMSIPLRELLEKHCGGIRGGWDNLLGVIPGGCSVPILTKDVCEHVLMDYDDLKDHLSGLGTAAVIVLDKSTDIVRA
IQRFSYFYKHESCGQCTPCREGTTWLLKVMDRFKAGQAGPREIDMLWELTKEVEGHTICALGDAAAWPIQGLIRNFRPEL
EARFQKFNEEIGSVSVGGWTPGATVGSGKVIGGPVPGSH

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0010181 FMN binding
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051287 NAD binding
GO:0051539 4 iron, 4 sulfur cluster binding

Cellular Component

None predicted.