MIA_05251_1

Protein

Length

274 amino acids

Protein function

EGGNOG:	0PG1Q	PGUG_05878	Probable N6-adenine methyltransferase
SGD closest match:	S000003233	EFM5	Protein-lysine N-methyltransferase EFM5
CGD closest match:	CAL0000196328	EFM5	Protein-lysine N-methyltransferase EFM5

Protein alignments

	%id	Aln length	E-value
MCA_04717_1	60.000%	275	2.01e-113	MCA_04717_1
A0A0J9XD96_GEOCN	48.315%	267	5.86e-86	Protein-lysine N-methyltransferase EFM5 OS=Geotrichum candidum GN=EFM5 PE=3 SV=1
Q6CB31_YARLI	44.444%	270	9.85e-76	Protein-lysine N-methyltransferase EFM5 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=EFM5 PE=3 SV=2
A0A060TC71_BLAAD	44.275%	262	7.63e-76	Protein-lysine N-methyltransferase EFM5 OS=Blastobotrys adeninivorans GN=EFM5 PE=3 SV=1
Q5A653_CANAL	48.162%	272	5.70e-75	Protein-lysine N-methyltransferase EFM5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EFM5 PE=3 SV=1
UniRef50_C5MCJ4	48.162%	272	2.07e-71	Protein-lysine N-methyltransferase EFM5 n=18 Tax=Saccharomycetales TaxID=4892 RepID=C5MCJ4_CANTT
EFM5_YEAST	45.693%	267	4.00e-71	Protein-lysine N-methyltransferase EFM5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EFM5 PE=1 SV=2
A0A1E4THZ9_9ASCO	42.248%	258	4.40e-59	Protein-lysine N-methyltransferase EFM5 OS=Tortispora caseinolytica NRRL Y-17796 GN=EFM5 PE=3 SV=1
A0A1E3PP55_9ASCO	39.716%	282	1.29e-57	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49524 PE=4 SV=1
A0A167FBU5_9ASCO	44.828%	203	9.88e-47	Aml1p OS=Sugiyamaella lignohabitans GN=AML1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0031

Protein family membership

Protein-lysine N-methyltransferase Efm5 (IPR019369)

Domains and repeats

None predicted.

Detailed signature matches

IPR019369

Protein-lysine N-methyltransferase Efm5
1. MF_03187 (Methyltr_...)
  
  7 - 270
  
  HAMAP
  MF_03187 (Methyltr_EFM5)
2. PF10237 (N6-adenine...)
  
  67 - 264
  
  Pfam
  PF10237 (N6-adenineMlase)
IPR002052

DNA methylase, N-6 adenine-specific, conserved site
1. PS00092 (N6_MTASE)
  
  187 - 193
  
  PROSITE patterns
  PS00092 (N6_MTASE)

no IPR

Unintegrated signatures

Coil

23 - 54

COILS
Coil (Coil)

Protein sequence

>MIA_05251_1
MSDLNLDSDDEPISLSAATLAALQEFQNEKKDRLEKFEQLYENSENRFSEKEISTDVIDKKIEDFEEDWNLSQFWYSNET
ADILAKEALKSIDVDLENLNEGKITKKLAIISAPSVYSAILRVLKEIKEKSSQDLSAKLNEILKNIYLLEFDARFRYLAV
TPDYFIQYDYNKPLSVPKELKGTIDSCVIDPPYISDECQTKVALTARYLMPQNESKTSSKVIVCTGERVSKTILKVYPGA
HMTTFFPEHANGLNNEFRCYSNFESSSWKFLTQE

GO term prediction

Biological Process

GO:0032259 methylation

Molecular Function

GO:0003676 nucleic acid binding
GO:0008168 methyltransferase activity

Cellular Component