MIA_05145_1

Protein

Length

453 amino acids

Protein function

EGGNOG:	0PFHA	FG03396.1	(Mfs) transporter
SGD closest match:	S000003885	YJR124C	Uncharacterized membrane protein YJR124C
CGD closest match:	CAL0000188365	orf19.4780	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
A0A0J9XIV9_GEOCN	52.561%	449	3.96e-136	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA20s01759g PE=4 SV=1
A0A060T8F0_BLAAD	50.000%	448	1.10e-128	ARAD1D03124p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D03124g PE=4 SV=1
Q5API4_CANAL	43.498%	446	6.45e-119	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4780 PE=4 SV=1
Q6C745_YARLI	45.695%	453	9.80e-118	YALI0E03872p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E03872g PE=4 SV=1
UniRef50_Q6C745	45.695%	453	2.27e-114	YALI0E03872p n=6 Tax=Saccharomycetales TaxID=4892 RepID=Q6C745_YARLI
A0A167CXG8_9ASCO	48.165%	436	3.06e-114	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_474 PE=4 SV=1
A0A1E3PCU1_9ASCO	46.606%	442	2.79e-102	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48136 PE=4 SV=1
YJ94_YEAST	36.449%	428	3.05e-71	Uncharacterized membrane protein YJR124C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJR124C PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1696
Predicted cleavage: 21

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
1 - 450
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 453

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  33 - 215
  
  Pfam
  PF07690 (MFS_1)
  
  277 - 445
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  1 - 450
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  24 - 443
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  36 - 434
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

369 - 424

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

288 - 306

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

180 - 190

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 26

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

79 - 89

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

19 - 238

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

246 - 449

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

214 - 267

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

48 - 58

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

327 - 345

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

124 - 153

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

449 - 453

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

191 - 213

TMHMM
TMhelix (TMhelix)

90 - 107

TMHMM
TMhelix (TMhelix)

111 - 133

TMHMM
TMhelix (TMhelix)

425 - 447

TMHMM
TMhelix (TMhelix)

154 - 176

TMHMM
TMhelix (TMhelix)

307 - 329

TMHMM
TMhelix (TMhelix)

344 - 366

TMHMM
TMhelix (TMhelix)

27 - 49

TMHMM
TMhelix (TMhelix)

59 - 78

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

268 - 287

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

425 - 448

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

346 - 368

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

191 - 213

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

59 - 78

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

27 - 47

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

307 - 326

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

154 - 179

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

90 - 123

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Residue annotation

putative substrate...

39F

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

42S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

43S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

44I

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

46L

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

47V

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

64M

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

67T

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

68L

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

71D

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

75S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

76Y

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

78L

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

79T

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

130I

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

131G

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

134K

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

135A

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

138E

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

139S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

142A

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

154Y

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

155A

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

158S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

159F

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

165T

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

282S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

285S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

286S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

289Q

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

291T

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

294S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

308L

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

312F

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

316G

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

319S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

323M

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

369R

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

372T

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

373S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

377I

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

381Q

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

382A

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

385S

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

396F

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

397M

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

400T

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

401N

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

404R

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

405T

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

408Q

putative substrate translocation pore
39F, 42S, 43S, 44I, 46L, 47V, 64M, 67T, 68L, 71D, 75S, 76Y, 78L, 79T, 130I, 131G, 134K, 135A, 138E, 139S, 142A, 154Y, 155A, 158S, 159F, 165T, 282S, 285S, 286S, 289Q, 291T, 294S, 308L, 312F, 316G, 319S, 323M, 369R, 372T, 373S, 377I, 381Q, 382A, 385S, 396F, 397M, 400T, 401N, 404R, 405T, 408Q
CDD
cd06174 (MFS)

Protein sequence

>MIA_05145_1
MLLNIFSHIGREFGVHTLANSSRDIKLLILIKIVRMIAFGQSSIFLVQFFHSHGYPTHLIGTFMSCTLIGDVVISYFLTL
NADRLGRRRVLVLGAILMTISGIIFATSNNFYVLLSAAILGVISPSGADIGPFKAIEESTLAHLVPKEHRNEIYAWYSFS
ATLATAFGNFSSGAFVHLVTSSRFNLSLLAAYKLIFILFALCGALKLVLSLLLTHNIETDEYLSPRQDLSDRAREHLPLL
TEEIPSQQGLLEKKKTISFLPNLSPESTVMAVKLSLLFALDSFASSLVQRTWMSYYISKKFSLSPEVLGSTFFSTGIISA
FTMLVSSSISKRLGPVLTMSLTHIPASLLLGFIPLPSTFMITFAIFIFRSCTSHMNIAPRQAFLSMVVKPSERTAFMGWT
NVVRTNSQIFGPSITGYLAGRDAQWISFVIAGVLKILYDLLIVVAFALKNYDY

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features