Protein

MIA_05135_1

Length
149 amino acids

Browser: contig07:828336-828786-

Protein function

EGGNOG:0PPBIFG00409.1cytidine deaminase
SGD closest match:S000004235CDD1Cytidine deaminase
CGD closest match:CAL0000191434orf19.3123.2Cytidine deaminase

Protein alignments

%idAln lengthE-value
A0A0J9XH25_GEOCN67.164%1349.76e-63Cytidine deaminase OS=Geotrichum candidum GN=BN980_GECA17s00648g PE=3 SV=1
MCA_00267_158.170%1536.40e-60MCA_00267_1
A0A1D8PMQ1_CANAL54.074%1351.16e-47Cytidine deaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3123.2 PE=3 SV=1
Q6C8T8_YARLI52.239%1341.53e-47Cytidine deaminase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D17072g PE=3 SV=1
UniRef50_B9WF4155.725%1315.32e-44Cytidine deaminase n=18 Tax=Fungi TaxID=4751 RepID=B9WF41_CANDC
A0A1E3PE04_9ASCO48.921%1392.70e-47Cytidine deaminase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53456 PE=3 SV=1
A0A060TAY5_BLAAD51.880%1332.30e-42Cytidine deaminase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B11220g PE=3 SV=1
A0A1E4TGY5_9ASCO47.917%1444.71e-42Cytidine deaminase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57364 PE=3 SV=1
CDD_YEAST44.030%1342.91e-35Cytidine deaminase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDD1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0660

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 149

Detailed signature matches

  1. Family IPR006262
    Cytidine deaminase, homotetrameric
    1. TIGR01354
  2. Domain IPR016193
    Cytidine deaminase-like
    1. SSF53927 (Cytidine ...)
  3. Domain IPR002125
    Cytidine and deoxycytidylate deaminase domain
    1. PF00383 (dCMP_cyt_d...)
    2. PS51747 (CYT_DCMP_D...)
  4. SITE IPR016192
    APOBEC/CMP deaminase, zinc-binding
    1. PS00903 (CYT_DCMP_D...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.14...
  2. cd01283 (cytidine_d...)

Residue annotation

  1. active site cd01283
  2. Zn binding site cd...
  3. catalytic motif cd...

Protein sequence

>MIA_05135_1
MFENIDSKAYAPFTLQEIRDLYDNVIRARSHAYAPYSHFRVGAVILTTDGQFITGCNVENASYPAGICAERTALVKAVSE
GVDPKTFRAIAVITDEKELCSPCGVCRQMIREFGTEISIVMFTSDGAQVKIMTLEQLLPMSFGPANLLK

GO term prediction

Biological Process

GO:0009972 cytidine deamination

Molecular Function

GO:0003824 catalytic activity
GO:0004126 cytidine deaminase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.