Protein

MIA_04997_1

Length
1,586 amino acids


Browser: contig07:400369-405187+

Protein function

EGGNOG:0PFBGFG05571.1metal resistance protein YCF1
SGD closest match:S000003938BPT1Bile pigment transporter 1
CGD closest match:CAL0000178329MLT1Multiple drug resistance-associated protein-like transporter 1

Protein alignments

%idAln lengthE-value
MCA_05647_264.390%15810.0MCA_05647_2
A0A0J9X5R3_GEOCN58.005%15740.0Similar to Saccharomyces cerevisiae YDR135C YCF1 Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family OS=Geotrichum candidum GN=BN980_GECA03s02595g PE=4 SV=1
UniRef50_A0A0J9X5R358.005%15740.0Similar to Saccharomyces cerevisiae YDR135C YCF1 Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5R3_GEOCN
A0A060TFR2_BLAAD42.521%15710.0ARAD1D25124p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D25124g PE=4 SV=1
A0A170QYS1_9ASCO41.282%15600.0ATP-binding cassette glutathione S-conjugate transporter YCF1 OS=Sugiyamaella lignohabitans GN=YCF1 PE=4 SV=1
A0A1E3PNZ7_9ASCO40.921%15640.0Multidrug resistance-associated protein 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81731 PE=4 SV=1
Q6C4N2_YARLI40.523%15670.0YALI0E25069p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E25069g PE=4 SV=1
A0A1E4TMK0_9ASCO43.101%13480.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30952 PE=4 SV=1
BPT1_YEAST41.367%13900.0Bile pigment transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BPT1 PE=1 SV=2
MLT1_CANAL38.478%14190.0Multiple drug resistance-associated protein-like transporter 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MLT1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0148

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1586

Detailed signature matches

    1. PS50929 (ABC_TM1F)
    2. PF00664 (ABC_membrane)
    3. SSF90123 (ABC trans...)
    1. SSF52540 (P-loop co...)
    1. PF00005 (ABC_tran)
    2. PS50893 (ABC_TRANSP...)
    1. SM00382 (AAA_5)
    1. PS00211 (ABC_TRANSP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PS51257 (PROKAR_LIP...)
  2. TRANSMEMBRANE (Tran...)
  3. cd03244 (ABCC_MRP_d...)
  4. cd03250 (ABCC_MRP_d...)
  5. mobidb-lite (disord...)

Residue annotation

  1. Walker A/P-loop cd...
  2. ATP binding site c...
  3. Q-loop/lid cd03250
  4. ABC transporter si...
  5. Walker B cd03250
  6. D-loop cd03250
  7. H-loop/switch regi...

Protein sequence

>MIA_04997_1
MDNKLSPSEQYHSLLPLLSSPLFSTSCSSSSLFSKLCGDTCWTALDSTGDLSPCFVNSVVLTVPPAIILLFGFLAPYSRV
ETRTSRTILPWYYYAKIILTIFAILCNISVGFFVYQSSFPLLSYALLTPLISAFLLLRVLAIHVLEDIQGVPSGILLIYW
LISIISYSIKFFTILPVNSTALTIPYAFLIFISISVFLLEYIPFKLLNQHRSQKQGIYSSYSSISQDQDDIESQSLDSPI
PSKALLDNADIFSRFAFAWMNPLISKAASGELTPSDLPVVDSNCNSTALANKFLRHWTSRTSDKISQLMLALFKSFGKLV
LLTGVFEFVTDLLGMAQPFLLRYLILFAQSYYSDDGTPPQAPEIGFYISLGMFSFAMAKTFARTHAFLVNINLMLSVRAA
LSSVIYKKALRITPAERQQKSTGEIVNLMSTDVIIIVRIFYMISTLWQAPIKLAMCLTGLYHLLGPSAFVGPSLIVAILP
LNSYMTSLLKKKRRKQMKYKDMRIRQTTELLTNIKSLKLYGWEPPLIDKINFIRNNKQLKNLKKLVVFSSIIDFLWVIIP
CIITTSSFAAFAYLENQPLTPDIVFPALSLFLMMNGPILDFPKTLVSSVNSLVSFQRVRDFLVSDELSNENFECIQPGAT
NIGDTTVLINNASFGWDHYIPYLKNIYYRACKGELSCIVGKVGCGKTSFLKSLLGELHCQSGSVKIRGNIAYVSQDMWLM
NASLRENILFGHKYDERFYNLTIESCALTPDIALLPDGDQTEIGEMGISLSGGQKARVSLARAVYARADIYLLDDPLSAV
DEHVAAHVMEKVLSSNGILGTKTRIFATNSIHALQRADTIVLLKDGCITQTSTFSAIMNPNAPESDLKTLINEFGRNSDD
DGMKSFETLETALEDDDQVEELNSSNINNDDEDYDVEDSKDSYQHEILRGSHRRTQSSHTLRRASLETLDNSFKGKGAKK
RQPESLHSTSPASTIVETMPLLAAPVKPLPKRTEKAEEKAEQGHVKWDVYKNYIQACNIKAVIITVAVVIISSLDSVTTK
FWLKHWSERNDEAGSNVNIRFYLGTYLGIGVTFALLGVARKAVVKIYCGLNASKKLHEEMLQAVAHAPMQFFETTPTGRI
INRFSSDIVELDEDLPSNFLEMIWVITDILISVVVIVYGAPMILFILFPLVGVYAYYQKYYASASRALKRLLVISRSPIY
SHFQETLTGSSTIRAFDQVERFEHINAVNLDYNLRAIFLFRGVNRWLSMRQQTIGSILTFATAIFVTYGAITRSISPGLI
GVVMGYSAVLSEDISYFIKTAVSLETSIIAVERIMEYCNLKGEAPAVIEATRPKPQWPERGTIEFVDYSTRYRDNLDLIL
QDISLSIRAQEKIGVVGRTGAGKSSLIMALFRIIEPAEGKIIIDGKNISTLGLADLRTHLSIIPQDSQIFEGTVRQNLDP
LSQHTEAELWHALKLAHLSKFVETTLSGGKEGLDATLAEGGSNISAGQKQLICLARALLHDSAILVLDEATASVDVTTDK
LIQETIRKEFKNKTIVTIAHRLNTIMDSDRILVLERGRIAEFDTPAKLLANPQSEFYALCKRGGLI

GO term prediction

Biological Process

GO:0006810 transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO:0016021 integral component of membrane