Protein

MIA_04986_1

Length
727 amino acids


Browser: contig07:360882-363230-

Protein function

EGGNOG:0PJJAPGUG_01312Anaphase-promoting complex subunit
SGD closest match:S000004117APC2Anaphase-promoting complex subunit 2
CGD closest match:CAL0000194665orf19.6821Anaphase promoting complex subunit 2

Protein alignments

%idAln lengthE-value
MCA_01233_147.928%7240.0MCA_01233_1
A0A0J9X6Q6_GEOCN42.065%5234.21e-141Similar to Saccharomyces cerevisiae YLR127C APC2 Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors OS=Geotrichum candidum GN=BN980_GECA04s00065g PE=3 SV=1
UniRef50_A0A0J9X6Q642.065%5238.60e-138Similar to Saccharomyces cerevisiae YLR127C APC2 Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6Q6_GEOCN
A0A060TIP1_BLAAD36.718%7195.87e-133ARAD1D48048p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D48048g PE=3 SV=1
A0A167CVI5_9ASCO35.867%7501.01e-130Anaphase promoting complex subunit 2 OS=Sugiyamaella lignohabitans GN=APC2 PE=3 SV=1
A0A1E3PHN9_9ASCO35.056%7166.57e-130Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83685 PE=3 SV=1
Q6C6Z8_YARLI33.661%7134.69e-115YALI0E04983p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E04983g PE=3 SV=1
A0A1E4TIH7_9ASCO29.013%6795.35e-82Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_55404 PE=3 SV=1
Q5ADM0_CANAL30.248%6051.60e-75Anaphase promoting complex subunit 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6821 PE=3 SV=1
APC2_YEAST22.064%5623.16e-21Anaphase-promoting complex subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APC2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0640

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 727

Detailed signature matches

    1. SSF75632 (Cullin ho...)
    2. PS50069 (CULLIN_2)
    3. SM00182 (cul_2)
    1. PF00888 (Cullin)
    1. SSF46785 ("Winged h...)
    1. SM01013 (APC2_2)
    2. PF08672 (ANAPC2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_04986_1
MNILDDSILSAVLEPSAQSQQPIQNDSTASIQTVLDWMHPDTLLSPPSDHTLAAIQALEKEGPETLRAVETQYLDLVRTH
FTHHAAPLLLQALASRSLPDLAAVIAESRRHYLYPVAFFSGAGEGCCERLADHFRALVVLTAPYTAVRPCLQKYLDSPGV
ALSAPADSVVHVLAAVADTYAPAGRVQDAVLAGFLADVTRVLVERYRGVWTREVRPEIDEWAARTLAPVAAARLFPQQTP
SAEDLTRIVDDVFLDVRIDELFDIIVDFPESRPALVDIKGCVRNSHQRAAIVNSLQQSCSRRLLHGGANTVDVLLGYISI
IRSLSLLEPRGVLLDKVARPIRRYLKDREDTIKEVLSGILGDKKSPIKELSQELVSLAVCKDAGPEEDDLKWQPDPLDAP
PDFSGGGSGAEHRGGVDIIGSLISIFDNKDVMVKELMRRFADTMLFSHEFDEETVLMTIELLKLKFGEDALGNLDVMIKD
MAESRRIDGLVHGRRDGEDKGSGVAAYFHADVISRLYWPRYNAVACVAPKEIEEQMKRFDGCFEKLKQGRELVWMGSLGS
VTLEIEVEGALREYVVSPEKASLICLFQETEQWTVEGLVKRLETSEGCVKSALLFWQKRGLVAQIGADEYTLGDKRRTVI
DDIGEAAAPQDPKEELRLYTSYIVGMLTNLGAVPAERIHSFLKVLVPAETPYTHTLAELQAFLDLLVEEEKLVVVGENYK
LLNAGAG

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

Molecular Function

GO:0031625 ubiquitin protein ligase binding

Cellular Component

None predicted.