MIA_04985_1

Protein

Length

694 amino acids

Protein function

EGGNOG:	0PJ5A	FG09490.1	Cell surface receptor MFS transporter

Protein alignments

	%id	Aln length	E-value
MCA_01539_1	63.007%	419	8.57e-173	MCA_01539_1
Q6C8N0_YARLI	55.792%	423	5.37e-144	YALI0D18359p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D18359g PE=4 SV=1
UniRef50_Q6C8N0	55.792%	423	1.24e-140	YALI0D18359p n=4 Tax=Saccharomycetales TaxID=4892 RepID=Q6C8N0_YARLI
A0A161HI19_9ASCO	54.306%	418	1.54e-135	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_3504 PE=4 SV=1
A0A060TC33_BLAAD	53.222%	419	1.67e-131	ARAD1B19778p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19778g PE=4 SV=1
A0A0J9XCW7_GEOCN	51.544%	421	2.29e-127	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA10s00197g PE=4 SV=1
A0A1E4TD00_9ASCO	44.601%	426	1.92e-109	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28534 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0169

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
210 - 624
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 600 694

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  246 - 550
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  210 - 624
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  228 - 623
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

287 - 431

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

627 - 694

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

496 - 501

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

552 - 562

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 224

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
Coil

86 - 113

COILS
Coil (Coil)
G3DSA:1.20.12...

217 - 417

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

418 - 678

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

456 - 474

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

586 - 604

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

247 - 265

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

524 - 528

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

264 - 286

TMHMM
TMhelix (TMhelix)

227 - 249

TMHMM
TMhelix (TMhelix)

529 - 551

TMHMM
TMhelix (TMhelix)

473 - 495

TMHMM
TMhelix (TMhelix)

502 - 524

TMHMM
TMhelix (TMhelix)

436 - 458

TMHMM
TMhelix (TMhelix)

563 - 585

TMHMM
TMhelix (TMhelix)

605 - 622

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

605 - 626

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

475 - 495

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

563 - 585

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

502 - 523

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

529 - 551

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

432 - 455

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

225 - 246

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

266 - 286

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

1 - 37

MobiDB Lite
mobidb-lite (disorder_prediction)

75 - 139

MobiDB Lite
mobidb-lite (disorder_prediction)

195 - 214

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

242W

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

245F

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

246A

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

247A

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

249S

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

250S

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

268S

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

271I

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

272L

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

275Y

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

279A

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

280P

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

282V

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

283A

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

332Q

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

333P

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

336L

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

337S

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

340T

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

341H

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

344D

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

356N

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

357A

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

360S

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

361V

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

367G

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

448Y

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

451L

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

452F

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

455Y

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

456S

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

459I

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

473A

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

477G

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

481I

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

484G

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

488V

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

540G

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

543S

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

544F

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

547L

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

551L

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

552E

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

555Q

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

566A

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

567C

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

570L

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

571W

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

574G

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

575Q

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

578G

putative substrate translocation pore
242W, 245F, 246A, 247A, 249S, 250S, 268S, 271I, 272L, 275Y, 279A, 280P, 282V, 283A, 332Q, 333P, 336L, 337S, 340T, 341H, 344D, 356N, 357A, 360S, 361V, 367G, 448Y, 451L, 452F, 455Y, 456S, 459I, 473A, 477G, 481I, 484G, 488V, 540G, 543S, 544F, 547L, 551L, 552E, 555Q, 566A, 567C, 570L, 571W, 574G, 575Q, 578G
CDD
cd06174 (MFS)

Protein sequence

>MIA_04985_1
MEDTKEPMKAVENEGAEDHTNATDTSPIPQQPLGMHAHLRASLQSLTASSLHANRLSLRHAEALNSLVSLGTGSLRSAME
PPVTGLEQQEPEAQQKERNRDDAEETNKEQTQGTKNQDKDQEQPARASLPQKTLADKKMREMVPSLVVDQEDDDLESDLA
SISRTSPAAPTNDPPRAASLVSNSLLIAPRADTGPARYLDDSDATPSDATPPPPAIEYRTYRRRWIGLAGLAVLNLLVSW
GWLSFAAISSTTAAWFGLASEAPVNWLSTAILFAYLASAPLVAPLLHARGVRGAMLVCAGLMVAGNWVRYAGTAVQKFGA
TMTGQILIGLAQPFALSAATHYTDLWFTSRSRVSANAIISVANPLGGAVAQLVGPPVVGDSPANLKTFVLITAIVASAGA
AVTAVAPGHPPSPPCASAAAPKLGLRASLKTLLRSPAFVVALCMFSIYVGLFNAYSTFINQIMEPYGYSADEAGYTGALL
IVAGLVGVGVVSPIVDRTHWYLPLFYVCLPVIAGCFVSLQYTATRDTQLAGPFVVSGVLGACSFSLLPTILEWVQEQTAP
VSPSVACTLLWCGGQLMGGVFIIAMDSLKYAPAEGDPPGNMRRALVFQAVWGCVGVVPLFFLRAIARPNSRVVLDRGSLP
PGAVVDGAEGALGFEADARLESRRSDLDVMSVSVDASSIEVPLEHVYADSGLKK

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features