Protein

MIA_04897_1

Length
342 amino acids


Browser: contig07:112574-113741+

Protein function

EGGNOG:0PK0UTWF1Actin monomer binding protein
SGD closest match:S000003312TWF1Twinfilin-1
CGD closest match:CAL0000176762COF1Cofilin

Protein alignments

%idAln lengthE-value
MCA_03590_145.614%3423.37e-70MCA_03590_1
A0A0J9XIT4_GEOCN37.791%3442.61e-49Similar to Saccharomyces cerevisiae YGR080W TWF1 Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton OS=Geotrichum candidum GN=BN980_GECA22s00241g PE=4 SV=1
UniRef50_A0A0J9XIT437.791%3445.34e-46Similar to Saccharomyces cerevisiae YGR080W TWF1 Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIT4_GEOCN
Q6C3H9_YARLI31.118%3312.10e-25YALI0E34687p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E34687g PE=4 SV=1
A0A060TH69_BLAAD41.727%1399.24e-24ARAD1D36410p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36410g PE=4 SV=1
A0A1E4TKC2_9ASCO32.660%2972.07e-21Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_59419 PE=4 SV=1
A0A167E6G9_9ASCO42.969%1283.44e-16Twf1p OS=Sugiyamaella lignohabitans GN=TWF1 PE=4 SV=1
A0A1E3PT46_9ASCO27.273%1431.68e-09Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45052 PE=4 SV=1
TWF1_YEAST45.652%464.00e-06Twinfilin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TWF1 PE=1 SV=1
A0A1D8PMW6_CANAL33.333%788.38e-06Cofilin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=COF1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4601

Protein family membership

None predicted.

Domains and repeats

1 50 100 150 200 250 300 342

Detailed signature matches

    1. PF00241 (Cofilin_ADF)
    2. PS51263 (ADF_H)
    3. SM00102 (adf_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF55753 (Actin dep...)
  2. cd11285 (ADF_Twf-N_...)
  3. mobidb-lite (disord...)

Residue annotation

  1. putative G-actin i...

Protein sequence

>MIA_04897_1
MASALNLSLSKSLEEAFSQLLATNQRALIAQIDGETVEHQQTIKGTADFEADFAEVAQHLEPDEPRYIIYNAAPASAPSY
VFILFVPDTAKVRAKMLYASSATALKRQLLGGAGGGDGGAGAAQTIFWTELGEVSREGWAAHVAHEALAAPLTREEQSLR
SPRGRDGGGPGPSGGSNVGMQFGADATAALEALGRADGGTVVLVIDVGAEQVHVGGAAAAAAGALRAEEFAADAAQFTVY
KPAGARNEDTAVFYTCPPATKVKERMVYATNFKSVRGHVARALGVQELERTYEGSSGEDVVGEYLDDERKAGAAGSGKPE
VVKAPRFSRPKAPGRLRREGAQ

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003779 actin binding

Cellular Component

GO:0005622 intracellular