Protein

MIA_04832_1

Length
1,255 amino acids

Browser: contig06:1090915-1094683+

Protein function

EGGNOG:0PIXIOPSBprotease
SGD closest match:S000004111YPS3Aspartic proteinase yapsin-3
CGD closest match:CAL0000192370SAP7Candidapepsin-7

Protein alignments

%idAln lengthE-value
MCA_05036_148.758%4432.76e-138MCA_05036_1
M1XFD0_GEOCN36.029%4082.67e-65Aspartic protease OS=Geotrichum candidum GN=YSP3 PE=3 SV=1
UniRef50_M1XFD036.029%4085.45e-62Aspartic protease n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=M1XFD0_GEOCN
A0A060TFI1_BLAAD33.095%4202.77e-59ARAD1D23562p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D23562g PE=3 SV=1
A0A167D1E2_9ASCO32.339%4361.37e-55Yps3p OS=Sugiyamaella lignohabitans GN=YPS3 PE=3 SV=1
A0A1E3PJQ9_9ASCO33.017%4218.62e-54Acid protease OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46336 PE=3 SV=1
YPS3_YEAST29.515%4543.37e-50Aspartic proteinase yapsin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPS3 PE=1 SV=1
Q6C558_YARLI32.746%3972.31e-50YALI0E20823p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E20823g PE=3 SV=1
CARP7_CANAL26.750%4003.57e-32Candidapepsin-7 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SAP7 PE=1 SV=2
A0A1E4TFI5_9ASCO24.533%3751.03e-14Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_25539 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0352
Predicted cleavage: 17

Protein family membership

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1255

Detailed signature matches

  1. Family IPR001461
    Aspartic peptidase A1 family
    1. PR00792 (PEPSIN)
  2. Domain IPR021109
    Aspartic peptidase domain
    1. G3DSA:2.40.70.10
    2. SSF50630 (Acid prot...)
  3. Domain IPR033121
    Peptidase family A1 domain
    1. PS51767 (PEPTIDASE_A1)
    2. PF00026 (Asp)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. TRANSMEMBRANE (Tran...)
  8. mobidb-lite (disord...)

Protein sequence

>MIA_04832_1
MICICAVATTVQASRYSGEKYVSFNLEKHYYRQNEYPRFSKRANLFDQPLINRLYYYTIKFSLGTPPQHFNLQIDTGSSD
IWVSSIMNPYCKEVISNSTIKQSLKISCGEQGLFDSNRSLTYRSKVDNMVLRYGDNSYAAGEFGSDILRIDNSEMKIIDM
EFIKAYEANTLGVFGIGMPGLEVSAHKPDNPFEYKNFPIRLQEAGFIDSIAYSMWLNTPTSTSGMVIFGGVDLKKFTPPL
VKIDLVPTFKNKILEFTIPASIINYFEAPCTTPFLLSDDPIVVLMEVGSTSSYLPNSVVTGLSEKLHMTQDEDGDYVRSC
NYTGDDTKFITIRLADFDLKIPVTHLILPKASLDGVPVLFDNGDPVCYLGIYPTDNPKFCSLGDNVLRSAYLVFDLDNKR
LAVAQTKTDSLESNILAIRPGKNGIPGSTDVYNAPSLFDTCKNYTYGNYSGISTFSTSLPITTKPSNFSTKPLPFIPSNI
TDILSKQNANTSFSTSSLKTQATAPNIVSTTFPSYITSTFNISSNFSTEDKIILTSSALLTSLNNSLVHTYSESLITSHE
KSYDLLSSTPSFTTNNKTWSFDPSVSTLSTSMKSTSTVLTSLNPSPSIGEKPVSLIQSTLFTTSVVASRTEIQTITSTGR
FSPSSTNIPLNIPLITSTRSSSFHVNDSITILSSFVSFNSRSFSDLPSRIKTSEAANQTESFNQNLAQPHTSVKSSVKED
LSTKDGMTSTYSNLTSVPIPSLNTGSKISTYISSTIQTIPITTNSLSNSNNGISGYIMPSSIADAFITSITRSSGTLGSL
GSTFSTRLPSTSNKAPGSTIFQSDSVSSLNGSQTSRIIISSKKLEFINSVNTTGISITFNMSQNSNTVSPLNTNINLIST
EEVYSQIPSKTSPVDSNKYIVTETSFLDNTFTTTETTMTNQETISLGLKTLNSFQSQTLNTILTDAINRPANNFLSHKDQ
TSNFKYISSPTLTSIKSLETEYPLTYETTMSDQKAQKINRQPEPYFKNNGDKSSNSLSVFVSSNTNLHAPPLSLTGDLAS
QNRFNDVLTSIASPVMSQITYDSPSSNQIQTRTITLDIIHPTTSMISEDQTQVTSNKNSYEDSGYSLKLETKNHHTLPFS
TKMFCETCDGNIFNNTRIFTERPRWINSNSSYLLSKTNNTVPQVSLQLTYKLNTSRESVFNAVTSVNNNVNFDVQSFHFP
LSPGHDLKIPKETSSLNKFEVNPLYNYQVNSANSLIAPGFWISLARIVLLLINTL

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004190 aspartic-type endopeptidase activity

Cellular Component

None predicted.