Protein

MIA_04698_1

Length
574 amino acids

Browser: contig06:749957-751682-

Protein function

EGGNOG:0PFMXFG09845.1Fatty acid desaturase
CGD closest match:CAL0000198953SLD1Delta 8-(E)-sphingolipid desaturase

Protein alignments

%idAln lengthE-value
MCA_02734_175.874%5720.0MCA_02734_1
A0A1E3PKG1_9ASCO60.926%5400.0Fatty acid/sphingolipid desaturase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51105 PE=4 SV=1
A0A167C092_9ASCO60.444%5410.0Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_3849 PE=4 SV=1
UniRef50_A0A167C09260.444%5410.0Uncharacterized protein n=4 Tax=Ascomycota TaxID=4890 RepID=A0A167C092_9ASCO
A0A0J9XF15_GEOCN54.466%5710.0Similar to Saccharomyces cerevisiae YNL111C CYB5 Cytochrome b5, involved in the sterol and lipid biosynthesis pathways OS=Geotrichum candidum GN=BN980_GECA13s03475g PE=4 SV=1
A0A060T2N5_BLAAD57.417%5730.0ARAD1C26796p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C26796g PE=4 SV=1
Q6C544_YARLI57.845%5290.0YALI0E21131p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E21131g PE=4 SV=1
A0A1E4TK93_9ASCO53.875%5290.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_762 PE=4 SV=1
SLD1_CANAL49.564%5730.0Delta 8-(E)-sphingolipid desaturase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SLD1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5196

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 574

Detailed signature matches

  1. Family IPR012171
    Fatty acid desaturase
    1. PIRSF015921 (FA_sph...)
  2. Domain IPR001199
    Cytochrome b5-like heme/steroid binding domain
    1. SSF55856 (Cytochrom...)
    2. PS50255 (CYTOCHROME...)
    3. PF00173 (Cyt-b5)
    4. G3DSA:3.10.12...
    5. SM01117 (Cyt_b5_2)
  3. Domain IPR005804
    Fatty acid desaturase domain
    1. PF00487 (FA_desaturase)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. cd03506 (Delta6-FAD...)

Residue annotation

  1. putative di-iron l...

Protein sequence

>MIA_04698_1
MTSLKDRPLSRDDIEDMIAQGQHVVVWHDRVLRLDSWLEFHPGGYKVVEHMVGRDATQEISVHHSDETLLKAQKYIIGKI
ELPWDNFRPPVQGGFFRTKAQMAITDEEEQKTIELVSPHRLQKNHKVSLYEFYRLPREADDSLDVEFESPTERIIEQYDR
DLLKKDRETFPLCDHQTQDAIVERFNKLHKLVLEKGLFQCNYWGYFREFCRISTLLTASYYTFHKHWLFISAVCLGLAWH
QMTFIAHDAGHQAITHWYQVDNLIGTLVADFCGGLSLGWWKRNHNVHHIITNDPVHDPDIQHLPFFAVSTRLFGDVFSTY
YERLLAFDIVAKYMIRVQNYTYYLILCFGRFNLYRLSLEYVLLGQGPRKGRGAWFRYLEFAGLGFFIYWFFYLVVACSIH
TAGERWMYVLVSHIVTMPVHVQITLSHFAMSTSDLGLDESFPQRQLRTTMDVDCPAWFDYVHGGLQFQAIHHLFPRMPRH
NFRKAQPYVIEFCKDVGLEYTIYGFHKGNMHVIDKLAEIAHQASILADCTGHLQQESFEFMVGKAADVNKSLQDAVISQK
RHQFDIEMSNRVRL

GO term prediction

Biological Process

GO:0006629 lipid metabolic process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

GO:0016021 integral component of membrane