Protein

MIA_04572_1

Length
423 amino acids


Browser: contig06:388875-390197+

Protein function

EGGNOG:0PHG6PGUG_03398Pseudouridine synthase
SGD closest match:S000005427RIB2Bifunctional protein RIB2
CGD closest match:CAL0000193029orf19.3177Bifunctional DRAP deaminase/tRNA pseudouridine synthase

Protein alignments

%idAln lengthE-value
MCA_04703_135.991%4391.03e-81MCA_04703_1
A0A060SZ03_BLAAD34.928%4185.95e-66ARAD1A15862p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A15862g PE=4 SV=1
UniRef50_Q74Z9834.211%4185.19e-64Pseudouridine synthase n=7 Tax=Saccharomycetaceae TaxID=4893 RepID=Q74Z98_ASHGO
A0A1E4TM99_9ASCO34.834%4227.02e-66Pseudouridine synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22508 PE=3 SV=1
A0A1E3PLI1_9ASCO33.937%4422.72e-65Pseudouridine synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50205 PE=3 SV=1
RIB2_YEAST33.412%4253.09e-61Bifunctional protein RIB2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIB2 PE=1 SV=1
A0A1D8PND6_CANAL33.333%4204.19e-60Bifunctional DRAP deaminase/tRNA pseudouridine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3177 PE=4 SV=1
A0A0J9XBT4_GEOCN31.895%5332.47e-60Similar to Saccharomyces cerevisiae YOL066C RIB2 Bifunctional enzyme with DRAP deaminase and tRNA:pseudouridine synthase activity OS=Geotrichum candidum GN=BN980_GECA08s03959g PE=4 SV=1
A0A167CCR8_9ASCO40.727%2752.27e-60Bifunctional DRAP deaminase/tRNA pseudouridine synthase RIB2 OS=Sugiyamaella lignohabitans GN=RIB2 PE=4 SV=1
Q6C1Z1_YARLI31.663%4398.50e-53YALI0F12199p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F12199g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7980
Predicted cleavage: 38

Protein family membership

None predicted.

Domains and repeats

1 50 100 150 200 250 300 350 423

Detailed signature matches

    1. SSF55120 (Pseudouri...)
    1. PF00849 (PseudoU_sy...)
Unintegrated signatures no IPR
Unintegrated signatures

Protein sequence

>MIA_04572_1
MTCMVYVENGLCKVRPYFATKRIWAKGRWLGRSVKEVLAAEFRNRSMAAHEEAMAAGHVALLRHSGLSKRAQRKAAGSAN
PDTPIESTFTVVRIQGPSEELAHAVLQNKDVVEYRAHVHEPPVTSSPGLAHWAHTADPSQWLAEVVVHETQDCLIICKPA
GIPVHPTGRYSRNTLTDLLEQALGYKVYASHRLDRLTSGLLVLGKTAPAAASLSERLREKSVSKEYVALVRGSFPPGPQT
VVTAPIFTTQFSDGSAKFAAGLRAAADCATQASTRDGPKPASTRFEGVWYDERRNVSLVRCAPLTGRTHQIRKHLAIAGH
AICDDPVYSHPAFPELHQAVLAALDGGSAQDQAVAAFEKIEQFVRQGMHDKMRPGETCGECGAPLFEDPDPRDLRISLHA
VRYSAVDGSFDYSVPLPTWARLS

GO term prediction

Biological Process

GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification

Molecular Function

GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity

Cellular Component

None predicted.