Protein

MIA_04522_1

Length
713 amino acids

Browser: contig06:239463-241605-

Protein function

EGGNOG:0PGQXPGUG_04722gamma-glutamyltranspeptidase
SGD closest match:S000004290ECM38Gamma-glutamyltransferase
CGD closest match:CAL0000184736CIS2Gamma-glutamyltransferase

Protein alignments

%idAln lengthE-value
MCA_04836_153.409%6160.0MCA_04836_1
A0A0J9XC32_GEOCN51.266%6320.0Similar to Saccharomyces cerevisiae YLR299W ECM38 Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme OS=Geotrichum candidum GN=BN980_GECA09s00406g PE=4 SV=1
UniRef50_A0A0J9XC3251.266%6320.0Similar to Saccharomyces cerevisiae YLR299W ECM38 Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XC32_GEOCN
A0A1E3PQK6_9ASCO49.837%6120.0Gamma-glutamyltranspeptidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45378 PE=4 SV=1
A0A167C9D5_9ASCO50.416%6010.0Gamma-glutamyltransferase OS=Sugiyamaella lignohabitans GN=ECM38 PE=4 SV=1
Q6CC93_YARLI45.997%6372.71e-168YALI0C11363p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C11363g PE=4 SV=1
A0A060T7R1_BLAAD45.733%6215.27e-153ARAD1C24002p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C24002g PE=4 SV=1
A0A1E4TFL7_9ASCO41.068%5998.17e-136Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12619 PE=4 SV=1
A0A1D8PC84_CANAL40.224%6242.55e-131Gamma-glutamyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CIS2 PE=4 SV=1
ECM38_YEAST40.159%6307.26e-113Gamma-glutamyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM38 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3011
Predicted cleavage: 18

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 713

Detailed signature matches

  1. Family IPR000101
    Gamma-glutamyltranspeptidase
    1. PF01019 (G_glu_tran...)
    2. PR01210 (GGTRANSPTASE)
  2. Domain IPR029055
    Nucleophile aminohydrolases, N-terminal
    1. SSF56235 (N-termina...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MIA_04522_1
MNLQKLPRPLPPPQIPRKIRSPHSTNGPAYQSYLKVRTALATAVLMIIATLTFLSLIIPYQPPPSSLLWPLLQPPPLSSS
SHLASLDRQHLFLDPFAIDETAPNHNRSYVFSKAAVSSDVPRCSTMAADILKQGGSAVDAAVTLALCLGSINSFSSGIGG
GGFMVVAQNANNSKAFNFRERAPAAAHKNMFKGNPFASKVGGLAVAIPGELAGLYAAFEQYSSGKLSWADLIRPVADLNR
NGFVVTEPLAHALTTVESVFIQAPENWNWLLTNAPLPPQDGQPPDLGHDSVGHTKVDKKTPPKGTLRTKVMGEIVRRPAF
AATLDLIAQNGSAAIFYDPNGPIAPNLVNAIQKSGGIATTADFANYSVEITSPQQTTLDLADGVFRKVYTMHNPSSGPVL
LFGLNVMEELHKKWGKTGSAEDQNTPGNSNNHWLDFEDIATQRLVETMKWMGASRSRLGDSADLNNSAAIAQITSKSFSS
KIAWSNVSDSQTHPWQYYDPAYESVDPHGTTHFSIVDENGLAVAMTTTVNLYFGALVADPVTGVLFNNEMDDFSVPGTSN
SFNLAPSIYNYVAPYKRPLSSCSPTIITAAHAPDGHDEAVEMVIGASGGSRILTTVLQTIVRKLFYRTSLAQAIQSPRIH
HQLLPHVAELEVGTPAHAAHALAARGHKVKYGPPGSVSNGIYRDLFGRERGAEHGKISAVADWWRKRGAPAGY

GO term prediction

Biological Process

GO:0006751 glutathione catabolic process

Molecular Function

GO:0036374 glutathione hydrolase activity

Cellular Component

None predicted.