Protein

MIA_04267_1

Length
455 amino acids

Browser: contig05:1238604-1239972+

Protein function

EGGNOG:0PGMAHOS2histone deacetylase
SGD closest match:S000003162HOS2Probable histone deacetylase HOS2
CGD closest match:CAL0000178362HOS2Histone deacetylase

Protein alignments

%idAln lengthE-value
MCA_06518_188.571%4550.0MCA_06518_1
A0A0J9X6T3_GEOCN87.061%4560.0Histone deacetylase OS=Geotrichum candidum GN=BN980_GECA04s04575g PE=3 SV=1
A0A060T5M3_BLAAD73.465%4560.0Histone deacetylase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08030g PE=3 SV=1
Q6CCW1_YARLI75.174%4310.0Histone deacetylase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C06061g PE=3 SV=1
A0A1E3PHN3_9ASCO69.803%4570.0Histone deacetylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52432 PE=3 SV=1
A0A167DW64_9ASCO79.898%3930.0Histone deacetylase OS=Sugiyamaella lignohabitans GN=HOS2 PE=3 SV=1
UniRef50_A0A167DW6479.898%3930.0Histone deacetylase n=68 Tax=Eukaryota TaxID=2759 RepID=A0A167DW64_9ASCO
A0A1E4TLW4_9ASCO66.009%4560.0Histone deacetylase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1312 PE=3 SV=1
A0A1D8PJ17_CANAL66.444%4500.0Histone deacetylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HOS2 PE=3 SV=1
HOS2_YEAST61.693%4490.0Probable histone deacetylase HOS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOS2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0089

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 455

Detailed signature matches

  1. Family IPR000286
    Histone deacetylase superfamily
    1. PR01270 (HDASUPER)
  2. Family IPR003084
    Histone deacetylase
    1. PR01271 (HISDACETLASE)
    2. PIRSF037913 (HDAC_I...)
  3. Domain IPR023801
    Histone deacetylase domain
    1. G3DSA:3.40.80...
    2. PF00850 (Hist_deacetyl)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52768 (Arginase/...)
  2. mobidb-lite (disord...)

Protein sequence

>MIA_04267_1
MVITTWEEATLSYDHKTTKEKPFYEDFLSSWKPRVSYHFNEEVSRFHFGVRHPMKPFRLMLTDHLVLGYKLHECMDLYRP
RRATREEILEFHDEAYIDFLQRVTPDNVKEFTKVFTKFNIGDDCPIFDGMYDYSSIYTGSSLDASRKLINEQSDIAINWS
GGLHHAKKFEASGFCYINDIVLGILNLLRYHPRVLYIDIDVHHGDGVQEAFYATDRVMTLSFHKYNGDYFPGTGNVDEIG
SGVGKHYSLNVPLRDGIDDDSYIRLFKSIVEPVLTSYQPGAIVLQCGADSLGCDRLGCFNLNTKAHAECVRFVRSFNMPM
MVVGGGGYTPRNVSRLWCLETSVCLDVELDSRLPASIPFVKYFAPDYSLFPNLSGKIDNKNSRKYLESVKTQVMEQLRYL
NGAPSIQMQEVPPDLMGYDQETDCAMADERNDRTADERDAEREAKDGARRGEQLD

GO term prediction

Biological Process

GO:0016575 histone deacetylation

Molecular Function

GO:0004407 histone deacetylase activity

Cellular Component

None predicted.