Protein

MIA_04230_1

Length
502 amino acids

Browser: contig05:1132449-1133958-

Protein function

EGGNOG:0PHBBFG05554.14-aminobutyrate aminotransferase
SGD closest match:S000003251UGA14-aminobutyrate aminotransferase
CGD closest match:CAL0000181031UGA14-aminobutyrate transaminase

Protein alignments

%idAln lengthE-value
MCA_01544_181.278%4540.0MCA_01544_1
A0A0J9XCM0_GEOCN74.834%4530.0Similar to Saccharomyces cerevisiae YGR019W UGA1 Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways OS=Geotrichum candidum GN=BN980_GECA09s02386g PE=3 SV=1
A0A1E3PG25_9ASCO68.874%4530.03-amino-2-methylpropionate transaminase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47567 PE=3 SV=1
A0A167EAW0_9ASCO68.584%4520.04-aminobutyrate transaminase OS=Sugiyamaella lignohabitans GN=UGA1 PE=3 SV=1
A0A060T0R9_BLAAD64.381%4520.0ARAD1C10538p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C10538g PE=3 SV=1
Q6C5G6_YARLI64.238%4530.0YALI0E18238p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E18238g PE=3 SV=1
UniRef50_B8MBS264.626%4410.04-aminobutyrate transaminase GatA n=74 Tax=Fungi TaxID=4751 RepID=B8MBS2_TALSN
GABAT_YEAST63.415%4510.04-aminobutyrate aminotransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UGA1 PE=1 SV=2
A0A1D8PH55_CANAL62.557%4380.04-aminobutyrate transaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UGA1 PE=3 SV=1
A0A1E4TFU7_9ASCO62.353%4250.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31469 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9713
Predicted cleavage: 22

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 502

Detailed signature matches

  1. Family IPR005814
    Aminotransferase class-III
    1. PS00600 (AA_TRANSFE...)
    2. cd00610 (OAT_like)
    3. PIRSF000521 (Transa...)
    4. PF00202 (Aminotran_3)
  2. Family IPR004631
    4-aminobutyrate aminotransferase, eukaryotic
    1. TIGR00699
  3. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
  4. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  5. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...

Residue annotation

  1. inhibitor-cofactor...
  2. pyridoxal 5'-phosp...
  3. catalytic residue ...

Protein sequence

>MIA_04230_1
MIKQVRPSTVTRPIGSAIKSTVGAAVAGSSKSFASVAEAYYPEEPAAPKIVSATIPGPENTKAIEKLTKVFDTRAAYFVA
DYYKSLGNYIVDVDGNALLDLYAQISSIALGYNNPAVLKAATSPEMAVALANRPALGNFPSNDYADILAEGILAAAPPGL
DKVWTDLSGSGANETAFKAAFMYKRAKERGFDADFSPEELESCMVNSKPGCPDLSILSFETAFHGRLFGSLSTTRSKPIH
KLDIPSFNWPKAPFPVLKYPLDKYAEENRAEEDRCLAEVERLIKTWPNPVAAVIIEPIQSEGGDNHTSAYFGQGLRDLTK
KLDVLFIVDEVQTGVGATGKFWAHEYWNLSDAPDIVTFSKKFQAAGYYFSEPKIVPNLPYRQFNTWCGDPSKAIIARAIY
QEIVANDLVARTAQVGEYLQGKLEALSTKFPTKIQNLRGKGTFIAWDMETPAARDSFLKDLRSNGVNCGGCGPKSVRLRP
ALVFEEKHADIFVDVVEKVLKL

GO term prediction

Biological Process

GO:0009448 gamma-aminobutyric acid metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0003867 4-aminobutyrate transaminase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.