Protein

MIA_04212_1

Length
573 amino acids

Browser: contig05:1090252-1091974+

Protein function

EGGNOG:0PFRJPGUG_03689Phosphoesterase
SGD closest match:S000004353DCR2Phosphatase DCR2
CGD closest match:CAL0000201620orf19.843Phosphoprotein phosphatase

Protein alignments

%idAln lengthE-value
MCA_01175_158.04%5720.0MCA_01175_1
A0A0J9XHJ7_GEOCN53.39%5750.0Similar to Saccharomyces cerevisiae YLR361C DCR2 Phosphoesterase involved in downregulation of the unfolded protein response OS=Geotrichum candidum GN=BN980_GECA18s01638g PE=4 SV=1
UniRef50_A0A0J9XHJ753.39%5750.0Similar to Saccharomyces cerevisiae YLR361C DCR2 Phosphoesterase involved in downregulation of the unfolded protein response n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHJ7_GEOCN
A0A161HIU6_9ASCO49.48%5804e-177Dcr2p OS=Sugiyamaella lignohabitans GN=DCR2 PE=4 SV=1
A0A060TDA4_BLAAD42.33%5742e-150ARAD1B23056p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B23056g PE=4 SV=1
A0A1E3PM62_9ASCO47.11%5544e-148Metallo-dependent phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45887 PE=4 SV=1
Q6C4V6_YARLI42.61%5821e-135YALI0E23364p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E23364g PE=4 SV=1
A0A1D8PGZ0_CANAL47.17%4241e-112Phosphoprotein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.843 PE=4 SV=1
A0A1E4TCK2_9ASCO43.55%4342e-91Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_45908 PE=4 SV=1
DCR2_YEAST34.65%6351e-69Phosphatase DCR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DCR2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9314

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 573

Detailed signature matches

  1. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
  2. Domain IPR004843
    Calcineurin-like phosphoesterase domain, ApaH type
    1. PF00149 (Metallophos)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. cd07383 (MPP_Dcr2)

Residue annotation

  1. putative active si...
  2. putative metal bin...

Protein sequence

>MIA_04212_1
MIRLSRLWTRQILKLVFGALAMLGMLFLVDRYYNFLPPAIQTRILLHQPGSVVIDIKLESCFLQSRCPVTDSVWFRVPKE
LSLNKKWSRKSYLYVKRVKEEELTSNMPVILDVALDTDKSNLLPTHILKDIEKEEEKEEKKQNISQLPPKEQNELALSKG
WKKEKYNIWIKRGKYNPFSSITSVDVLFGHDAQDPRPGWQLREGFIDNDQKALPRITVRVGPKQEHPHVELRIHKTGKFK
ILQLADLHFSTDYGVCRDLFPPDKEGSKSCKADPRTLEFVEKVLDQEQPDYVVLTGDQIYGETSPDSETSILKVVAPLIR
RKIPYSMVMGNHDDEGGSLSRKEQVALISDLPYSLTQVGPANVSGYGNYVQQVLGPRSDNPALTFYFLDSHSRSPNNKLH
PGYAWIEQDQLDFVKSSYNHLKEKQDQYSHIHMSMAFMHIPFTEYVSNKPIVGQAREPVTASKFNLGTRDVLASVGVSVV
SVGHDHVNDYCMFHDKKADEGPLNRDTAMWLCFGGATGEGGYGGYGGYERRIRLFEIDTQAATIASWKLLHEHPDARIDE
QVLVKDGKAALST

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

None predicted.